Computer Aided Development of Nucleic Acid Applications in Nanotechnologies

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F22%3A00569260" target="_blank" >RIV/68081707:_____/22:00569260 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15640/22:73618680

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/10.1002/smll.202204408" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/smll.202204408</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/smll.202204408" target="_blank" >10.1002/smll.202204408</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Computer Aided Development of Nucleic Acid Applications in Nanotechnologies

Popis výsledku v původním jazyce

Utilization of nucleic acids (NAs) in nanotechnologies and nanotechnology-related applications is a growing field with broad application potential, ranging from biosensing up to targeted cell delivery. Computer simulations are useful techniques that can aid design and speed up development in this field. This review focuses on computer simulations of hybrid nanomaterials composed of NAs and other components. Current state-of-the-art molecular dynamics simulations, empirical force fields (FFs), and coarse-grained approaches for the description of deoxyribonucleic acid and ribonucleic acid are critically discussed. Challenges in combining biomacromolecular and nanomaterial FFs are emphasized. Recent applications of simulations for modeling NAs and their interactions with nano- and biomaterials are overviewed in the fields of sensing applications, targeted delivery, and NA templated materials. Future perspectives of development are also highlighted.

Název v anglickém jazyce

Computer Aided Development of Nucleic Acid Applications in Nanotechnologies

Popis výsledku anglicky

Utilization of nucleic acids (NAs) in nanotechnologies and nanotechnology-related applications is a growing field with broad application potential, ranging from biosensing up to targeted cell delivery. Computer simulations are useful techniques that can aid design and speed up development in this field. This review focuses on computer simulations of hybrid nanomaterials composed of NAs and other components. Current state-of-the-art molecular dynamics simulations, empirical force fields (FFs), and coarse-grained approaches for the description of deoxyribonucleic acid and ribonucleic acid are critically discussed. Challenges in combining biomacromolecular and nanomaterial FFs are emphasized. Recent applications of simulations for modeling NAs and their interactions with nano- and biomaterials are overviewed in the fields of sensing applications, targeted delivery, and NA templated materials. Future perspectives of development are also highlighted.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20506 - Coating and films

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Small

ISSN

1613-6810

e-ISSN

1613-6829

Svazek periodika

18

Číslo periodika v rámci svazku

49

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

24

Strana od-do

—

Kód UT WoS článku

000865565900001

EID výsledku v databázi Scopus

2-s2.0-85139398261