Adsorption, 2D-condensation, and redox reactions of bile acids on the hanging mercury drop electrode

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F23%3A00583488" target="_blank" >RIV/68081707:_____/23:00583488 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/23:10472926

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1572665723007476?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1572665723007476?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jelechem.2023.117887" target="_blank" >10.1016/j.jelechem.2023.117887</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Adsorption, 2D-condensation, and redox reactions of bile acids on the hanging mercury drop electrode

Popis výsledku v původním jazyce

Bile acids (BAs) are natural surfactants thanks to the facial amphiphilic character of the steroid skeleton. For the first time, the electrochemical and adsorption behaviour of selected bile acids differing in the number of hydroxyl groups on the steroid skeleton lithocholic acid (3 alpha-OH), deoxycholic acid (3 alpha-and 12 alpha-OH), and cholic acid (3 alpha-, 7 alpha-and 12 alpha-OH) was investigated on hanging mercury drop electrode (HMDE) in mixed Britton Robinson buffer: methanol (9:1) media. In cyclic voltammetry, all BAs yielded a negative signal at the potential of ca-1.4 V with intensity depending on pH of the solution. Further, sharp tensammetric signals confirming adsorption/desorption or re-organization processes of the adsorbed molecules were observed. AC voltammetric measurements revealed two-dimensional (2D) condensation of lithocholic acid in the pH range 12.0-7.0 visualized by the formation of a capacitance pit. Adsorption of the other studied BAs was indicated by the AC current density decrease. Measurements of differential capacitance dependencespotential (C-E curves) revealed this behaviour to be concentration and temperature dependent. A study on effect of halides (Cl-, Br-, I-) on the adsorption of bile acids showed involvement of primarily hydrophobic interactions in the BA interaction with the HMDE surface.

Název v anglickém jazyce

Adsorption, 2D-condensation, and redox reactions of bile acids on the hanging mercury drop electrode

Popis výsledku anglicky

Bile acids (BAs) are natural surfactants thanks to the facial amphiphilic character of the steroid skeleton. For the first time, the electrochemical and adsorption behaviour of selected bile acids differing in the number of hydroxyl groups on the steroid skeleton lithocholic acid (3 alpha-OH), deoxycholic acid (3 alpha-and 12 alpha-OH), and cholic acid (3 alpha-, 7 alpha-and 12 alpha-OH) was investigated on hanging mercury drop electrode (HMDE) in mixed Britton Robinson buffer: methanol (9:1) media. In cyclic voltammetry, all BAs yielded a negative signal at the potential of ca-1.4 V with intensity depending on pH of the solution. Further, sharp tensammetric signals confirming adsorption/desorption or re-organization processes of the adsorbed molecules were observed. AC voltammetric measurements revealed two-dimensional (2D) condensation of lithocholic acid in the pH range 12.0-7.0 visualized by the formation of a capacitance pit. Adsorption of the other studied BAs was indicated by the AC current density decrease. Measurements of differential capacitance dependencespotential (C-E curves) revealed this behaviour to be concentration and temperature dependent. A study on effect of halides (Cl-, Br-, I-) on the adsorption of bile acids showed involvement of primarily hydrophobic interactions in the BA interaction with the HMDE surface.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Projekt

<a href="/cs/project/GA19-11268S" target="_blank" >GA19-11268S: Elektrochemické metody: Nové přístupy pro charakterizaci a analýzu steroidů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Electroanalytical Chemistry

ISSN

1572-6657

e-ISSN

1873-2569

Svazek periodika

950

Číslo periodika v rámci svazku

DEC 1 2023

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

117887

Kód UT WoS článku

001109764500001

EID výsledku v databázi Scopus

2-s2.0-85175810964