Evolution and functioning of an X-A balance sex-determining system in hops

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F25%3A00637715" target="_blank" >RIV/68081707:_____/25:00637715 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.nature.com/articles/s41477-025-02017-6" target="_blank" >https://www.nature.com/articles/s41477-025-02017-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41477-025-02017-6" target="_blank" >10.1038/s41477-025-02017-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Evolution and functioning of an X-A balance sex-determining system in hops

Popis výsledku v původním jazyce

Chromosomal sex-determining systems with male heterogamety include actively male-determining-Y and X-A balance systems, both of which are found in animals and plants. The sex-determining genes have been identified in several active-Y plant systems, but the evolution and functioning of X-A balance systems remains mysterious. Here we sequenced and compared the genomes of two hop species. The evolution of the hop X-A balance system involved an ancient recombination suppression event across a large X chromosome region shared by both species. In one species, an autosome fused to this ancestral sex chromosome, and recombination was subsequently suppressed again. The two evolutionary strata created in this neo-X have degenerated to different degrees and evolved correspondingly different dosage compensation levels that correlate with histone modification patterns. Finally, we identified an X-specific ETR1-like ethylene receptor in the ancestral X region. Its dosage may affect sex determination, as part of the counting mechanism of this X-A balance system.

Název v anglickém jazyce

Evolution and functioning of an X-A balance sex-determining system in hops

Popis výsledku anglicky

Chromosomal sex-determining systems with male heterogamety include actively male-determining-Y and X-A balance systems, both of which are found in animals and plants. The sex-determining genes have been identified in several active-Y plant systems, but the evolution and functioning of X-A balance systems remains mysterious. Here we sequenced and compared the genomes of two hop species. The evolution of the hop X-A balance system involved an ancient recombination suppression event across a large X chromosome region shared by both species. In one species, an autosome fused to this ancestral sex chromosome, and recombination was subsequently suppressed again. The two evolutionary strata created in this neo-X have degenerated to different degrees and evolved correspondingly different dosage compensation levels that correlate with histone modification patterns. Finally, we identified an X-specific ETR1-like ethylene receptor in the ancestral X region. Its dosage may affect sex determination, as part of the counting mechanism of this X-A balance system.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

<a href="/cs/project/GA22-00301S" target="_blank" >GA22-00301S: Dynamika genomů v kontextu evoluce pohlavních chromozomů u rodu Humulus</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nature Plants

ISSN

2055-026X

e-ISSN

2055-0278

Svazek periodika

11

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

14

Strana od-do

1339-1352

Kód UT WoS článku

001511353700001

EID výsledku v databázi Scopus

2-s2.0-105008393918