Acytota and the evolution of complexity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F25%3A00642915" target="_blank" >RIV/68081707:_____/25:00642915 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/article/10.1007/s00249-025-01802-7" target="_blank" >https://link.springer.com/article/10.1007/s00249-025-01802-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00249-025-01802-7" target="_blank" >10.1007/s00249-025-01802-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Acytota and the evolution of complexity

Popis výsledku v původním jazyce

The overall complexity of organisms increases during the course of evolution, starting with the first self-replicating molecules, followed by prokaryotes and eukaryotes, first unicellular and later multicellular. We present an opinion that non-cellular genetic entities such as transposable elements, plasmids, viruses and viroids, although originally parasitic, selfish and sometimes destructive elements, may contribute to the increase of complexity. We propose that non-cellular genetic elements impose (parasitic) pressure on the cooperative genes of cellular organisms, driving the sequence of evolutionary transitions from the first cooperative replicators to multicellular life forms, and have suggested that they belong to a separate kingdom of life, the Acytota. The complexity increase is probably caused by the high proliferation capacity of these non-cellular genetic elements, their frequent horizontal gene transfer, participation in parasite-host arms races, formation of epigenetic silencing mechanisms as well as the ability to build genetic regulatory networks. Simultaneously, these elements contribute to complexity by supplying genetic material via domestication, genome rearrangements, and dispersal of regulatory elements. Complexity has not only increased during evolution, there are also examples of simplification, both during chemical evolution (in prebiotic chemistry) and the evolution of parasites. Therefore, we describe the ups and downs of organism complexity and discuss the reasons for the general dominant upward trend, namely coevolution and the interaction of existing modules.

Název v anglickém jazyce

Acytota and the evolution of complexity

Popis výsledku anglicky

The overall complexity of organisms increases during the course of evolution, starting with the first self-replicating molecules, followed by prokaryotes and eukaryotes, first unicellular and later multicellular. We present an opinion that non-cellular genetic entities such as transposable elements, plasmids, viruses and viroids, although originally parasitic, selfish and sometimes destructive elements, may contribute to the increase of complexity. We propose that non-cellular genetic elements impose (parasitic) pressure on the cooperative genes of cellular organisms, driving the sequence of evolutionary transitions from the first cooperative replicators to multicellular life forms, and have suggested that they belong to a separate kingdom of life, the Acytota. The complexity increase is probably caused by the high proliferation capacity of these non-cellular genetic elements, their frequent horizontal gene transfer, participation in parasite-host arms races, formation of epigenetic silencing mechanisms as well as the ability to build genetic regulatory networks. Simultaneously, these elements contribute to complexity by supplying genetic material via domestication, genome rearrangements, and dispersal of regulatory elements. Complexity has not only increased during evolution, there are also examples of simplification, both during chemical evolution (in prebiotic chemistry) and the evolution of parasites. Therefore, we describe the ups and downs of organism complexity and discuss the reasons for the general dominant upward trend, namely coevolution and the interaction of existing modules.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10610 - Biophysics

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Biophysics Journal With Biophysics Letters

ISSN

0175-7571

e-ISSN

1432-1017

Svazek periodika

54

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

11

Strana od-do

625-635

Kód UT WoS článku

001600753300001

EID výsledku v databázi Scopus

2-s2.0-105019979122