Secreted proteins as a fundamental source for biomarker discovery
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F12%3A00376119" target="_blank" >RIV/68081715:_____/12:00376119 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1002/pmic.201100346" target="_blank" >http://dx.doi.org/10.1002/pmic.201100346</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/pmic.201100346" target="_blank" >10.1002/pmic.201100346</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Secreted proteins as a fundamental source for biomarker discovery
Popis výsledku v původním jazyce
We discuss the proteins secreted by three progenitor cell types (smooth muscle, endothelial and cardiac progenitor cells) and two adult cell types (neonatal rat ventrical myocytes and smooth muscle cells) which can be relevant to cardiovascular researchand which have been recently published in the literature. We found, at least for secretome studies included in this review, that secretomes of progenitor and adult cells overlap by 48% but the secretomes are very distinct among progenitor cell themselvesas well as between adult cells. As expected, many proteins have been identified as biomarkers in cancer but 18 proteins (out of 62) have been tested as biomarkers in cardiovascular diseases as well.
Název v anglickém jazyce
Secreted proteins as a fundamental source for biomarker discovery
Popis výsledku anglicky
We discuss the proteins secreted by three progenitor cell types (smooth muscle, endothelial and cardiac progenitor cells) and two adult cell types (neonatal rat ventrical myocytes and smooth muscle cells) which can be relevant to cardiovascular researchand which have been recently published in the literature. We found, at least for secretome studies included in this review, that secretomes of progenitor and adult cells overlap by 48% but the secretomes are very distinct among progenitor cell themselvesas well as between adult cells. As expected, many proteins have been identified as biomarkers in cancer but 18 proteins (out of 62) have been tested as biomarkers in cardiovascular diseases as well.
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
CB - Analytická chemie, separace
OECD FORD obor
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Návaznosti výsledku
Projekt
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Návaznosti
Z - Vyzkumny zamer (s odkazem do CEZ)
Ostatní
Rok uplatnění
2012
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Proteomics
ISSN
1615-9853
e-ISSN
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Svazek periodika
12
Číslo periodika v rámci svazku
4-5
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
14
Strana od-do
722-735
Kód UT WoS článku
000302151800018
EID výsledku v databázi Scopus
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