Speciation analysis of mercury employing volatile species generation: Approaches to reliable determination in blood and hair

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F21%3A00544232" target="_blank" >RIV/68081715:_____/21:00544232 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/21:10436731

Výsledek na webu

<a href="http://hdl.handle.net/11104/0321263" target="_blank" >http://hdl.handle.net/11104/0321263</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.microc.2021.106606" target="_blank" >10.1016/j.microc.2021.106606</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Speciation analysis of mercury employing volatile species generation: Approaches to reliable determination in blood and hair

Popis výsledku v původním jazyce

A simple and short (7 min) two-stage extraction procedure was proposed for simultaneous determination of Hg2+, MeHg+ and EtHg+ in human blood. Acceptable extraction efficiency of Hg species without their inter-conversions was confirmed by analysis of certified reference materials resulting in recoveries better than 90% (Hg2+, MeHg+) and 80% for EtHg+, respectively. HPLC separation and following post-column volatile species generation (VSG) steps were optimized to achieve the best analytical performance employing ICP-MS detection. VSG step enhances sensitivity 30–40 times and improves limits of detection (LOD) by a factor of five in comparison with the setup without VSG step. Extraction selectivity of MeHg+ from human hair matrix was verified by HPLC-ICP-MS and applied to both certified reference material and real samples.

Název v anglickém jazyce

Speciation analysis of mercury employing volatile species generation: Approaches to reliable determination in blood and hair

Popis výsledku anglicky

A simple and short (7 min) two-stage extraction procedure was proposed for simultaneous determination of Hg2+, MeHg+ and EtHg+ in human blood. Acceptable extraction efficiency of Hg species without their inter-conversions was confirmed by analysis of certified reference materials resulting in recoveries better than 90% (Hg2+, MeHg+) and 80% for EtHg+, respectively. HPLC separation and following post-column volatile species generation (VSG) steps were optimized to achieve the best analytical performance employing ICP-MS detection. VSG step enhances sensitivity 30–40 times and improves limits of detection (LOD) by a factor of five in comparison with the setup without VSG step. Extraction selectivity of MeHg+ from human hair matrix was verified by HPLC-ICP-MS and applied to both certified reference material and real samples.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GA18-01116S" target="_blank" >GA18-01116S: Pokročilé přístupy ke generování těkavých sloučenin se spektrometrickou detekcí: ultrastopové stanovení a speciační analýza Cd, Hg, As a Se</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Microchemical Journal

ISSN

0026-265X

e-ISSN

1095-9149

Svazek periodika

170

Číslo periodika v rámci svazku

NOV

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

106606

Kód UT WoS článku

000696315700003

EID výsledku v databázi Scopus

2-s2.0-85111008172