Labeling strategies for analysis of oligosaccharides and glycans by capillary electrophoresis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F23%3A00571292" target="_blank" >RIV/68081715:_____/23:00571292 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/23:00130705

Výsledek na webu

<a href="https://hdl.handle.net/11104/0342550" target="_blank" >https://hdl.handle.net/11104/0342550</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.trac.2023.117068" target="_blank" >10.1016/j.trac.2023.117068</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Labeling strategies for analysis of oligosaccharides and glycans by capillary electrophoresis

Popis výsledku v původním jazyce

Capillary electrophoresis represents a powerful separation technique that has been widely accepted in oligosaccharide and glycan analysis. However, due to their low electrophoretic mobility as well as thenlack of chromophore or fluorophore in their native structure, appropriate modification of the saccharide molecule is required before separation and detection. In this review, we summarize the labeling strategiesnused for oligosaccharide/glycan analysis followed by electrophoretic separation published between 2010 and mid-2022. The review is divided by the labeling mechanism and part of the saccharide molecule used for modification. Although most labeling for CE-based applications is done with 8-aminopyrene-1,3,6-trisulfonic acid trisodium salt, we have also summarized less common, rare, and very recently developed tags with applicability in glycomics.

Název v anglickém jazyce

Labeling strategies for analysis of oligosaccharides and glycans by capillary electrophoresis

Popis výsledku anglicky

Capillary electrophoresis represents a powerful separation technique that has been widely accepted in oligosaccharide and glycan analysis. However, due to their low electrophoretic mobility as well as thenlack of chromophore or fluorophore in their native structure, appropriate modification of the saccharide molecule is required before separation and detection. In this review, we summarize the labeling strategiesnused for oligosaccharide/glycan analysis followed by electrophoretic separation published between 2010 and mid-2022. The review is divided by the labeling mechanism and part of the saccharide molecule used for modification. Although most labeling for CE-based applications is done with 8-aminopyrene-1,3,6-trisulfonic acid trisodium salt, we have also summarized less common, rare, and very recently developed tags with applicability in glycomics.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GA22-00236S" target="_blank" >GA22-00236S: Vývoj nových fluorescenčních značek pro elektroforetické analýzy glykoproteinů asociovaných s rakovinou prsu</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

TrAC-Trends in Analytical Chemistry

ISSN

0165-9936

e-ISSN

1879-3142

Svazek periodika

163

Číslo periodika v rámci svazku

June

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

117068

Kód UT WoS článku

000991776100001

EID výsledku v databázi Scopus

2-s2.0-85153888628