Ag/Fe3O4 bifunctional nanocomposite for SERS detection of non-steroidal anti-inflammation drug diclofenac

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F24%3A00600255" target="_blank" >RIV/68081715:_____/24:00600255 - isvavai.cz</a>

Výsledek na webu

<a href="https://vjs.ac.vn/index.php/jst/article/view/20157/2543255740" target="_blank" >https://vjs.ac.vn/index.php/jst/article/view/20157/2543255740</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.15625/2525-2518/20157" target="_blank" >10.15625/2525-2518/20157</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ag/Fe3O4 bifunctional nanocomposite for SERS detection of non-steroidal anti-inflammation drug diclofenac

Popis výsledku v původním jazyce

In this work, a bifunctional nanocomposite based on silver and iron oxide nanoparticles (AgNPs/Fe3O4) was prepared and then used as SERS substrate (surface-enhanced Raman spectroscopy) for sensing diclofenac which is one of the most widely used non-steroid anti-inflammation drugs. AgNPs/Fe3O4 nanocomposite was synthesized by combining co-precipitation of iron oxide and in-situ reduction of silver nanoparticles. Morphology and structural studies revealed a conjugated structure in which silver nanoparticles (80 nm in diameter) were surrounded by iron oxide nanoparticles (18 nm in diameter). There is a slight blue-shift in position of plasmon peak from 405 nm for silver nanoparticles to 375 nm for AgNPs/Fe3O4 nanocomposite. Even the saturation magnetization (Ms) of the Ag/Fe3O4 nanocomposite only reached 28 emu.g-1 but still good enough for immobilizing nanocomposite structures onto the substrate. The use of AgNPs/Fe3O4 nanocomposite as SERS substrate for sensing application was demonstrated with using diclofenac as a model. The detection limit and enhancement factor of the SERS-based diclofenac sensor were found to be 10-12 M and 2.6×1010, respectively. Such kind of bifunctional nanocomposite will probably help us to avoid time-consuming process to immobilize metal nanoparticles onto the surface, and also allow us to regenerate the substrate for multiple uses.

Název v anglickém jazyce

Ag/Fe3O4 bifunctional nanocomposite for SERS detection of non-steroidal anti-inflammation drug diclofenac

Popis výsledku anglicky

In this work, a bifunctional nanocomposite based on silver and iron oxide nanoparticles (AgNPs/Fe3O4) was prepared and then used as SERS substrate (surface-enhanced Raman spectroscopy) for sensing diclofenac which is one of the most widely used non-steroid anti-inflammation drugs. AgNPs/Fe3O4 nanocomposite was synthesized by combining co-precipitation of iron oxide and in-situ reduction of silver nanoparticles. Morphology and structural studies revealed a conjugated structure in which silver nanoparticles (80 nm in diameter) were surrounded by iron oxide nanoparticles (18 nm in diameter). There is a slight blue-shift in position of plasmon peak from 405 nm for silver nanoparticles to 375 nm for AgNPs/Fe3O4 nanocomposite. Even the saturation magnetization (Ms) of the Ag/Fe3O4 nanocomposite only reached 28 emu.g-1 but still good enough for immobilizing nanocomposite structures onto the substrate. The use of AgNPs/Fe3O4 nanocomposite as SERS substrate for sensing application was demonstrated with using diclofenac as a model. The detection limit and enhancement factor of the SERS-based diclofenac sensor were found to be 10-12 M and 2.6×1010, respectively. Such kind of bifunctional nanocomposite will probably help us to avoid time-consuming process to immobilize metal nanoparticles onto the surface, and also allow us to regenerate the substrate for multiple uses.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Vietnam Journal of Science and Technology

ISSN

2525-2518

e-ISSN

2815-5874

Svazek periodika

62

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

VN - Vietnamská socialistická republika

Počet stran výsledku

11

Strana od-do

931-941

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85208604360