Menopausa, vliv změny hladiny hormonů na modulaci RR a QT intervalů během spánku

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F05%3A00028800" target="_blank" >RIV/68081731:_____/05:00028800 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Menopause, hormone replacement and RR and QT modulation during sleep

Popis výsledku v původním jazyce

The main aim of the present study was to evaluate sleep-related RR and QT changes: (1) with the physiological decline in female hormones occurring with menopause, and (2) after hormone replacement therapy with estrogen and progesterone (HRT). We analyzedECG recordings from 14 post-menopausal women (48-61 years old) who underwent polysomnography before HRT (T1) and after 6 month of HRT (T2). Eight of the post-menopausal women (48-54 years) In all subjects, mean RR interval, mean QT interval and QTc, were obtained from 1-min recordings selected from wakefulness, stage 2 REM sleep. Result: In both pre-menopausal and post-menopausal women the RR interval was shorter during REM sleep compare to wakefulness. The QTc interval was increased during REM sleep compared to wakefulness. Conclusion: Sleep-related RR and QT changes in women are not altered by menopausal status nor by post-menopausal hormonal replacement with estrogen and progesterone.

Název v anglickém jazyce

Menopause, hormone replacement and RR and QT modulation during sleep

Popis výsledku anglicky

The main aim of the present study was to evaluate sleep-related RR and QT changes: (1) with the physiological decline in female hormones occurring with menopause, and (2) after hormone replacement therapy with estrogen and progesterone (HRT). We analyzedECG recordings from 14 post-menopausal women (48-61 years old) who underwent polysomnography before HRT (T1) and after 6 month of HRT (T2). Eight of the post-menopausal women (48-54 years) In all subjects, mean RR interval, mean QT interval and QTc, were obtained from 1-min recordings selected from wakefulness, stage 2 REM sleep. Result: In both pre-menopausal and post-menopausal women the RR interval was shorter during REM sleep compare to wakefulness. The QTc interval was increased during REM sleep compared to wakefulness. Conclusion: Sleep-related RR and QT changes in women are not altered by menopausal status nor by post-menopausal hormonal replacement with estrogen and progesterone.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FS - Lékařská zařízení, přístroje a vybavení

OECD FORD obor

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Projekt

<a href="/cs/project/GA102%2F05%2F0402" target="_blank" >GA102/05/0402: Metody měření a vyhodnocení vlastností regulace krevního oběhu</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Sleep Medicine

ISSN

1389-9457

e-ISSN

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Svazek periodika

6

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

561-566

Kód UT WoS článku

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EID výsledku v databázi Scopus

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