Left bundle branch pacing compared to left ventricular septal myocardial pacing increases interventricular dyssynchrony but accelerates left ventricular lateral wall depolarization

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F21%3A00544671" target="_blank" >RIV/68081731:_____/21:00544671 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/21:00075085 RIV/00216208:11120/21:43921450 RIV/00216305:26220/21:PU141465 RIV/00064173:_____/21:N0000040

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1547527121004021?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1547527121004021?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.hrthm.2021.04.025" target="_blank" >10.1016/j.hrthm.2021.04.025</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Left bundle branch pacing compared to left ventricular septal myocardial pacing increases interventricular dyssynchrony but accelerates left ventricular lateral wall depolarization

Popis výsledku v původním jazyce

Background: Nonselective His-bundle pacing (nsHBp), nonselective left bundle branch pacing (nsLBBp), and left ventricular septal myocardial pacing (LVSP) are recognized as physiological pacing techniques. Objective: The purpose of this study was to compare differences in ventricular depolarization between these techniques using ultra-high-frequency electrocardiography (UHF-ECG). Methods: In patients with bradycardia, nsHBp, nsLBBp (confirmed concomitant left bundle branch [LBB] and myocardial capture), and LVSP (pacing in left ventricular [LV] septal position without proven LBB capture) were performed. Timings of ventricular activations in precordial leads were displayed using UHF-ECG, and electrical dyssynchrony (e-DYS) was calculated as the difference between the first and last activation. Duration of local depolarization (Vd) was determined as width of the UHF-QRS complex at 50% of its amplitude. Results: In 68 patients, data were collected during nsLBBp (35), LVSP (96), and nsHBp (55). nsLBBp resulted in larger e-DYS than did LVSP and nsHBp [– 24 ms (–28,–19) vs –12 ms (–16,–9) vs 10 ms (7,14), respectively, P <.001]. nsLBBp produced similar values of Vd in leads V5–V8 (36-43 ms vs 38-43 ms, P = NS in all leads) but longer Vd in leads V1–V4 (47–59 ms vs 41–44 ms, P <.05) as nsHBp. LVSP caused prolonged Vd in leads V1–V8 compared to nsHBp and longer Vd in leads V5–V8 compared to nsLBBp (44–51 ms vs 36–43 ms, P <.05) regardless of R-wave peak time in lead V5 or QRS morphology in lead V1 present during LVSP. Conclusion: nslbbp preserves physiological LV depolarization but increases interventricular electrical dyssynchrony. LV lateral wall depolarization during LVSP is prolonged, but interventricular synchrony is preserved.

Název v anglickém jazyce

Left bundle branch pacing compared to left ventricular septal myocardial pacing increases interventricular dyssynchrony but accelerates left ventricular lateral wall depolarization

Popis výsledku anglicky

Background: Nonselective His-bundle pacing (nsHBp), nonselective left bundle branch pacing (nsLBBp), and left ventricular septal myocardial pacing (LVSP) are recognized as physiological pacing techniques. Objective: The purpose of this study was to compare differences in ventricular depolarization between these techniques using ultra-high-frequency electrocardiography (UHF-ECG). Methods: In patients with bradycardia, nsHBp, nsLBBp (confirmed concomitant left bundle branch [LBB] and myocardial capture), and LVSP (pacing in left ventricular [LV] septal position without proven LBB capture) were performed. Timings of ventricular activations in precordial leads were displayed using UHF-ECG, and electrical dyssynchrony (e-DYS) was calculated as the difference between the first and last activation. Duration of local depolarization (Vd) was determined as width of the UHF-QRS complex at 50% of its amplitude. Results: In 68 patients, data were collected during nsLBBp (35), LVSP (96), and nsHBp (55). nsLBBp resulted in larger e-DYS than did LVSP and nsHBp [– 24 ms (–28,–19) vs –12 ms (–16,–9) vs 10 ms (7,14), respectively, P <.001]. nsLBBp produced similar values of Vd in leads V5–V8 (36-43 ms vs 38-43 ms, P = NS in all leads) but longer Vd in leads V1–V4 (47–59 ms vs 41–44 ms, P <.05) as nsHBp. LVSP caused prolonged Vd in leads V1–V8 compared to nsHBp and longer Vd in leads V5–V8 compared to nsLBBp (44–51 ms vs 36–43 ms, P <.05) regardless of R-wave peak time in lead V5 or QRS morphology in lead V1 present during LVSP. Conclusion: nslbbp preserves physiological LV depolarization but increases interventricular electrical dyssynchrony. LV lateral wall depolarization during LVSP is prolonged, but interventricular synchrony is preserved.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30201 - Cardiac and Cardiovascular systems

Projekt

<a href="/cs/project/NU21-02-00584" target="_blank" >NU21-02-00584: Využití vysokofrekvenčního EKG k predikci negativní remodelace levé komory srdeční při chronické kardiostimulaci</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Heart Rhythm

ISSN

1547-5271

e-ISSN

1556-3871

Svazek periodika

18

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

1281-1289

Kód UT WoS článku

000680052000010

EID výsledku v databázi Scopus

2-s2.0-85106369108