Analysis of bacteria using surface-enhanced Raman scattering

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Analysis of bacteria using surface-enhanced Raman scattering

Popis výsledku v původním jazyce

A key challenge in clinical practice is to fight against pathogenic microorganisms. Treating infections is often complicated by the growing resistance of microorganisms to antibiotics while developing new antibiotics remains limited. The effective lifetime of existing antibiotics can be prolonged by avoiding the overuse of broad-spectrum antibiotics which can be achieved through better diagnostics of pathogens. Raman spectroscopy (RS) has emerged as a promising alternative method for identifying pathogenic bacteria, as demonstrated in various studies. On the other hand, the main limitation of RS is its low sensitivity, which can lead to extended measurement times or difficulty in detecting pathogens effectively. However, signal intensity can be significantly amplified through advanced RS techniques, such as surface-enhanced Raman spectroscopy (SERS). In biological applications, the SERS method can be utilized in different ways. One uses a SERS substrate (a planar surface with a nanostructured design). Another approach incorporates nanoparticles directly into the sample. The last approach is using so-called SERS tags.

Název v anglickém jazyce

Analysis of bacteria using surface-enhanced Raman scattering

Popis výsledku anglicky

A key challenge in clinical practice is to fight against pathogenic microorganisms. Treating infections is often complicated by the growing resistance of microorganisms to antibiotics while developing new antibiotics remains limited. The effective lifetime of existing antibiotics can be prolonged by avoiding the overuse of broad-spectrum antibiotics which can be achieved through better diagnostics of pathogens. Raman spectroscopy (RS) has emerged as a promising alternative method for identifying pathogenic bacteria, as demonstrated in various studies. On the other hand, the main limitation of RS is its low sensitivity, which can lead to extended measurement times or difficulty in detecting pathogens effectively. However, signal intensity can be significantly amplified through advanced RS techniques, such as surface-enhanced Raman spectroscopy (SERS). In biological applications, the SERS method can be utilized in different ways. One uses a SERS substrate (a planar surface with a nanostructured design). Another approach incorporates nanoparticles directly into the sample. The last approach is using so-called SERS tags.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10406 - Analytical chemistry

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

LA64. Sborník příspěvků multioborové konference LASER64

ISBN

978-80-87441-34-3

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

7-11

Název nakladatele

Ústav přístrojové techniky AV ČR

Místo vydání

Brno

Místo konání akce

Třešť

Datum konání akce

13. 11. 2024

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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