Unveiling the mystery of déj? vu: The structural anatomy of déj? vu

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081740%3A_____%2F12%3A00382689" target="_blank" >RIV/68081740:_____/12:00382689 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.cortex.2012.03.004" target="_blank" >http://dx.doi.org/10.1016/j.cortex.2012.03.004</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.cortex.2012.03.004" target="_blank" >10.1016/j.cortex.2012.03.004</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Unveiling the mystery of déj? vu: The structural anatomy of déj? vu

Popis výsledku v původním jazyce

Déj? vu (DV) is a widespread, fascinating and mysterious human experience. It occurs both in health and in disease, notably as an aura of temporal lobe epilepsy. This feeling of inappropriate familiarity has attracted interest from psychologists and neuroscientists for over a century, but still there is no widely agreed explanation for the phenomenon of non-pathological DV. Here we investigated differences in brain morphology between healthy subjects with and without DV using a novel multivariate neuroimaging technique, Source-Based Morphometry. The analysis revealed a set of cortical (mainly mesiotemporal) and subcortical regions in which there was significantly less gray matter in subjects reporting DV. In these regions gray matter volume was inversely correlated with the frequency of DV. Our results demonstrate a structural correlate of DV in healthy individuals for the first time and support a neurological explanation for the phenomenon. We hypothesis that the observed local gray m

Název v anglickém jazyce

Unveiling the mystery of déj? vu: The structural anatomy of déj? vu

Popis výsledku anglicky

Déj? vu (DV) is a widespread, fascinating and mysterious human experience. It occurs both in health and in disease, notably as an aura of temporal lobe epilepsy. This feeling of inappropriate familiarity has attracted interest from psychologists and neuroscientists for over a century, but still there is no widely agreed explanation for the phenomenon of non-pathological DV. Here we investigated differences in brain morphology between healthy subjects with and without DV using a novel multivariate neuroimaging technique, Source-Based Morphometry. The analysis revealed a set of cortical (mainly mesiotemporal) and subcortical regions in which there was significantly less gray matter in subjects reporting DV. In these regions gray matter volume was inversely correlated with the frequency of DV. Our results demonstrate a structural correlate of DV in healthy individuals for the first time and support a neurological explanation for the phenomenon. We hypothesis that the observed local gray m

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Cortex

ISSN

0010-9452

e-ISSN

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Svazek periodika

48

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

IT - Italská republika

Počet stran výsledku

4

Strana od-do

1240-1243

Kód UT WoS článku

000308121900013

EID výsledku v databázi Scopus

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