Mitogenomics and evolutionary history of rodent whipworms (Trichuris spp.) originating from three biogeographic regions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F21%3A00543610" target="_blank" >RIV/68081766:_____/21:00543610 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41210/21:88288 RIV/00216224:14310/21:00122104

Výsledek na webu

<a href="https://www.mdpi.com/2075-1729/11/6/540" target="_blank" >https://www.mdpi.com/2075-1729/11/6/540</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/life11060540" target="_blank" >10.3390/life11060540</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Mitogenomics and evolutionary history of rodent whipworms (Trichuris spp.) originating from three biogeographic regions

Popis výsledku v původním jazyce

Trichuris spp. is a widespread nematode which parasitizes a wide range of mammalian hosts including rodents, the most diverse mammalian order. However, genetic data on rodent whipworms are still scarce, with only one published whole genome (Trichuris muris) despite an increasing demand for whole genome data. We sequenced the whipworm mitogenomes from seven rodent hosts belonging to three biogeographic regions (Palearctic, Afrotropical, and Indomalayan), including three previously described species: Trichuris cossoni, Trichuris arvicolae, and Trichuris mastomysi. We assembled and annotated two complete and five almost complete mitogenomes (lacking only the long non-coding region) and performed comparative genomic and phylogenetic analyses. All the mitogenomes are circular, have the same organisation, and consist of 13 protein-coding, 2 rRNA, and 22 tRNA genes. The phylogenetic analysis supports geographical clustering of whipworm species and indicates that T. mastomysi found in Eastern Africa is able to infect multiple closely related rodent hosts. Our results are informative for species delimitation based on mitochondrial markers and could be further used in studies on phylogeny, phylogeography, and population genetics of rodent whipworms.

Název v anglickém jazyce

Mitogenomics and evolutionary history of rodent whipworms (Trichuris spp.) originating from three biogeographic regions

Popis výsledku anglicky

Trichuris spp. is a widespread nematode which parasitizes a wide range of mammalian hosts including rodents, the most diverse mammalian order. However, genetic data on rodent whipworms are still scarce, with only one published whole genome (Trichuris muris) despite an increasing demand for whole genome data. We sequenced the whipworm mitogenomes from seven rodent hosts belonging to three biogeographic regions (Palearctic, Afrotropical, and Indomalayan), including three previously described species: Trichuris cossoni, Trichuris arvicolae, and Trichuris mastomysi. We assembled and annotated two complete and five almost complete mitogenomes (lacking only the long non-coding region) and performed comparative genomic and phylogenetic analyses. All the mitogenomes are circular, have the same organisation, and consist of 13 protein-coding, 2 rRNA, and 22 tRNA genes. The phylogenetic analysis supports geographical clustering of whipworm species and indicates that T. mastomysi found in Eastern Africa is able to infect multiple closely related rodent hosts. Our results are informative for species delimitation based on mitochondrial markers and could be further used in studies on phylogeny, phylogeography, and population genetics of rodent whipworms.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

<a href="/cs/project/GA18-19629S" target="_blank" >GA18-19629S: Srovnávací genomika hybridizace parazitů s ohledem na míru divergence hostitelů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Life

ISSN

2075-1729

e-ISSN

2075-1729

Svazek periodika

11

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

15

Strana od-do

540

Kód UT WoS článku

000666554900001

EID výsledku v databázi Scopus

2-s2.0-85108657141