Specific anti-SVCV antibodies in hybrids of common carp (Cyprinus carpio) and gibel carp (Carassius gibelio) reflect heterosis advantage and genetic breakdown

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F24%3A00587922" target="_blank" >RIV/68081766:_____/24:00587922 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/24:00136899

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0044848624007816?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0044848624007816?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.aquaculture.2024.741320" target="_blank" >10.1016/j.aquaculture.2024.741320</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Specific anti-SVCV antibodies in hybrids of common carp (Cyprinus carpio) and gibel carp (Carassius gibelio) reflect heterosis advantage and genetic breakdown

Popis výsledku v původním jazyce

Spring viraemia of carp virus (SVCV) is a disease with a serious economic impact on the farming of cyprinid fish. High susceptibility to SVCV has been documented mostly in common carp (Cyprinus carpio), whilst gibel carp (Carassius gibelio) is a weakly susceptible species. Specific anti-SVCV antibodies were analyzed in pure lines of common carp and gibel carp, and various generations of F1 and post-F1 hybrids. Specifically, we focused on anti-SVCV antibodies in weakly susceptible F1 hybrids and highly infected backcross and F2 hybrids, hypothesizing that the level of anti-SVCV antibodies will reflect heterosis advantage in F1 generations and hybrid breakdown in post-F1 generations. Backcross generations with common carp exhibited the most frequently symptomatic infections, followed by pure common carp. The high capacity of susceptible common carp to produce anti-SVCV antibodies was reported, whilst gibel carp expressed almost undetectable levels of anti-SVCV antibodies. We found the very good capacity of F1 hybrids to produce anti-SVCV antibodies, suggesting heterosis advantage. In contrast, we revealed different patterns of anti-SVCV antibodies production between maternal backcrosses (having parents with the same mtDNA – here, gibel carp) and paternal backcrosses (having parents with different mtDNA, i.e., resulting from reciprocal crosses of F1 hybrids with gibel carp mtDNA and pure common carp). Whilst both maternal backcross generations and the F2 generation of hybrids tended to produce low anti-SVCV antibodies, both paternal backcross generations expressed levels of anti SVCV-antibodies similar to those of highly susceptible common carp. The low capacity to produce anti-SVCV antibodies in F2 hybrids may be interpreted as a potential consequence of genetic disruption. However, the different capacity to induce an adaptive response in paternal hybrids and maternal hybrids (with mtDNA C. gibelio) may be interpreted as potential compensation for the cyto-nuclear breakdown hypothesized for paternal hybrids when coping with viral infection. Alternatively, the genetic background of hybrid fish, i.e. a combination of the genes of highly susceptible common carp and of less susceptible gibel carp in the hybrid genome may be responsible for this pattern.

Název v anglickém jazyce

Specific anti-SVCV antibodies in hybrids of common carp (Cyprinus carpio) and gibel carp (Carassius gibelio) reflect heterosis advantage and genetic breakdown

Popis výsledku anglicky

Spring viraemia of carp virus (SVCV) is a disease with a serious economic impact on the farming of cyprinid fish. High susceptibility to SVCV has been documented mostly in common carp (Cyprinus carpio), whilst gibel carp (Carassius gibelio) is a weakly susceptible species. Specific anti-SVCV antibodies were analyzed in pure lines of common carp and gibel carp, and various generations of F1 and post-F1 hybrids. Specifically, we focused on anti-SVCV antibodies in weakly susceptible F1 hybrids and highly infected backcross and F2 hybrids, hypothesizing that the level of anti-SVCV antibodies will reflect heterosis advantage in F1 generations and hybrid breakdown in post-F1 generations. Backcross generations with common carp exhibited the most frequently symptomatic infections, followed by pure common carp. The high capacity of susceptible common carp to produce anti-SVCV antibodies was reported, whilst gibel carp expressed almost undetectable levels of anti-SVCV antibodies. We found the very good capacity of F1 hybrids to produce anti-SVCV antibodies, suggesting heterosis advantage. In contrast, we revealed different patterns of anti-SVCV antibodies production between maternal backcrosses (having parents with the same mtDNA – here, gibel carp) and paternal backcrosses (having parents with different mtDNA, i.e., resulting from reciprocal crosses of F1 hybrids with gibel carp mtDNA and pure common carp). Whilst both maternal backcross generations and the F2 generation of hybrids tended to produce low anti-SVCV antibodies, both paternal backcross generations expressed levels of anti SVCV-antibodies similar to those of highly susceptible common carp. The low capacity to produce anti-SVCV antibodies in F2 hybrids may be interpreted as a potential consequence of genetic disruption. However, the different capacity to induce an adaptive response in paternal hybrids and maternal hybrids (with mtDNA C. gibelio) may be interpreted as potential compensation for the cyto-nuclear breakdown hypothesized for paternal hybrids when coping with viral infection. Alternatively, the genetic background of hybrid fish, i.e. a combination of the genes of highly susceptible common carp and of less susceptible gibel carp in the hybrid genome may be responsible for this pattern.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

<a href="/cs/project/GA19-10088S" target="_blank" >GA19-10088S: Genetická disrupce u mezidruhových hybridů kaprovitých ryb: její dopad na kondici-asociované znaky, imunitu a parazitární zátěž</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Aquaculture

ISSN

0044-8486

e-ISSN

1873-5622

Svazek periodika

593

Číslo periodika v rámci svazku

December

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

741320

Kód UT WoS článku

001275773300001

EID výsledku v databázi Scopus

2-s2.0-85198829260