Novel LDPE/vermiculite/ciclopiroxolamine hybrid nanocomposites: Structure, surface properties, and antifungal activity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68145535%3A_____%2F21%3A00544969" target="_blank" >RIV/68145535:_____/21:00544969 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989100:27640/21:10245820 RIV/70883521:28110/21:63526164

Výsledek na webu

<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/app.50232" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/app.50232</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/app.50232" target="_blank" >10.1002/app.50232</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Novel LDPE/vermiculite/ciclopiroxolamine hybrid nanocomposites: Structure, surface properties, and antifungal activity

Popis výsledku v původním jazyce

The increasing number of indwelling medical materials and devices are connected with infections caused by yeast, especially Candida albicans. This pathogen produces undesirable biofilms on synthetic materials. Since antimicrobial polymer nanocomposites present one of the promising possibility of reduction of such biofilms, therefore this study is focused on developing nanocomposite based on low density polyethylene (LDPE) with clay mineral vermiculite as an active carrier for antifungal compound. The set of LDPE/vermiculite nanocomposite with increasing amount of antifungal nanofiller was prepared. As antifungal agent was selected generally used active substance ciclopiroxolamine. The structure of all prepared samples was studied by X-ray diffraction analysis and Fourier transforms infrared spectroscopy. Further thermal properties of polyethylene/clay nanocomposites were investigated by thermogravimetric analysis and the surface properties were evaluated by light optical microscopy, scanning electron microscopy and atomic force microscopy. From mentioned characteristics, we conclude that presence of nanofiller in LDPE primarily causes shift of thermal degradation to higher temperatures and increasing of microhardness. All prepared LDPE nanocomposites possess an excellent and prolonged antifungal activity against Candida albicans.

Název v anglickém jazyce

Novel LDPE/vermiculite/ciclopiroxolamine hybrid nanocomposites: Structure, surface properties, and antifungal activity

Popis výsledku anglicky

The increasing number of indwelling medical materials and devices are connected with infections caused by yeast, especially Candida albicans. This pathogen produces undesirable biofilms on synthetic materials. Since antimicrobial polymer nanocomposites present one of the promising possibility of reduction of such biofilms, therefore this study is focused on developing nanocomposite based on low density polyethylene (LDPE) with clay mineral vermiculite as an active carrier for antifungal compound. The set of LDPE/vermiculite nanocomposite with increasing amount of antifungal nanofiller was prepared. As antifungal agent was selected generally used active substance ciclopiroxolamine. The structure of all prepared samples was studied by X-ray diffraction analysis and Fourier transforms infrared spectroscopy. Further thermal properties of polyethylene/clay nanocomposites were investigated by thermogravimetric analysis and the surface properties were evaluated by light optical microscopy, scanning electron microscopy and atomic force microscopy. From mentioned characteristics, we conclude that presence of nanofiller in LDPE primarily causes shift of thermal degradation to higher temperatures and increasing of microhardness. All prepared LDPE nanocomposites possess an excellent and prolonged antifungal activity against Candida albicans.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Applied Polymer Science

ISSN

0021-8995

e-ISSN

1097-4628

Svazek periodika

138

Číslo periodika v rámci svazku

16

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

50232

Kód UT WoS článku

000585313600001

EID výsledku v databázi Scopus

2-s2.0-85096811786