Newborns health in the Danube Region: Environment, biomonitoring, interventions and economic benefits in a large prospective birth cohort study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F16%3A00458317" target="_blank" >RIV/68378041:_____/16:00458317 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11690/16:10322453

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.envint.2015.12.009" target="_blank" >http://dx.doi.org/10.1016/j.envint.2015.12.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.envint.2015.12.009" target="_blank" >10.1016/j.envint.2015.12.009</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Newborns health in the Danube Region: Environment, biomonitoring, interventions and economic benefits in a large prospective birth cohort study

Popis výsledku v původním jazyce

BACKGROUND: nThe EU strategy for the Danube Region addresses numerous challenges including environment, health and socioeconomic disparities. Estimating the burden of environmental exposures on early-life health is a growing research area in Europe which has major public health implications, but the data from the Danube Region are largely missing.nAIM: nThis review presents an inventory of current environmental challenges, related early-life health risks, and knowledge gaps in the Danube Region, based on publicly available databases, registers, and literature, as a rationale for a new integrated project. nMETHODS: nExperts in environmental epidemiology, human biomonitoring and social science in collaboration with clinicians propose to establish a new large multi-center birth cohort of mother-child pairs from Danube countries, measure biomarkers of exposure and health in biological samples at birth, collect centrally measured climate, air and water pollution data, conduct pre- and postnatal surveys on lifestyle, indoor exposures, noise, occupation, socio-economic status, risk-averting behavior, and preferences; and undertake clinical examinations of children at and after birth. Effects of multiple environmental exposures on fetal and child growth, respiratory, allergic, immunologic, and neurodevelopmental health outcomes will be estimated. nCONCLUSIONS: nThe proposed project would provide novel estimates of the burden of early childhood diseases attributable to environmental exposures and assess health impacts of different intervention scenarios in the Danube Region. nn

Název v anglickém jazyce

Newborns health in the Danube Region: Environment, biomonitoring, interventions and economic benefits in a large prospective birth cohort study

Popis výsledku anglicky

BACKGROUND: nThe EU strategy for the Danube Region addresses numerous challenges including environment, health and socioeconomic disparities. Estimating the burden of environmental exposures on early-life health is a growing research area in Europe which has major public health implications, but the data from the Danube Region are largely missing.nAIM: nThis review presents an inventory of current environmental challenges, related early-life health risks, and knowledge gaps in the Danube Region, based on publicly available databases, registers, and literature, as a rationale for a new integrated project. nMETHODS: nExperts in environmental epidemiology, human biomonitoring and social science in collaboration with clinicians propose to establish a new large multi-center birth cohort of mother-child pairs from Danube countries, measure biomarkers of exposure and health in biological samples at birth, collect centrally measured climate, air and water pollution data, conduct pre- and postnatal surveys on lifestyle, indoor exposures, noise, occupation, socio-economic status, risk-averting behavior, and preferences; and undertake clinical examinations of children at and after birth. Effects of multiple environmental exposures on fetal and child growth, respiratory, allergic, immunologic, and neurodevelopmental health outcomes will be estimated. nCONCLUSIONS: nThe proposed project would provide novel estimates of the burden of early childhood diseases attributable to environmental exposures and assess health impacts of different intervention scenarios in the Danube Region. nn

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Environment International

ISSN

0160-4120

e-ISSN

—

Svazek periodika

88

Číslo periodika v rámci svazku

mar.

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

112-122

Kód UT WoS článku

000371359300016

EID výsledku v databázi Scopus

2-s2.0-84951788913