Systematic review of the use of the lymphocyte cytokinesis-block micronucleus assay to measure DNA damage induced by exposure to polycyclic aromatic hydrocarbons

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F16%3A00469929" target="_blank" >RIV/68378041:_____/16:00469929 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.mrrev.2016.07.009" target="_blank" >http://dx.doi.org/10.1016/j.mrrev.2016.07.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mrrev.2016.07.009" target="_blank" >10.1016/j.mrrev.2016.07.009</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Systematic review of the use of the lymphocyte cytokinesis-block micronucleus assay to measure DNA damage induced by exposure to polycyclic aromatic hydrocarbons

Popis výsledku v původním jazyce

The effect of exposure to polycyclic aromatic hydrocarbons (PAHs) to induce micronuclei (MN) measured using the lymphocytes cytokinesis-block micronucleus (CBMN) assay were evaluated in 34 studies according to the exposure: 20 studies in coke oven workers, 7 studies in different occupational exposures as alluminium industry workers, rubber factory workers, road construction workers, airport workers and diesel exposed workers, 6 studies on environmentaly exposed groups as police, volunteers and children. nnReviewed papers indicate that the CBMN assay is a sensitive biomarker of PAHs exposure in polluted air. Reviewed studies confirmed previous conclusions, that the frequency of MN measured using the lymphocyte CBMN is not significantly affected by smoking, females are more sensitive to PAHs than males, the frequency of MN is increased with age.

Název v anglickém jazyce

Systematic review of the use of the lymphocyte cytokinesis-block micronucleus assay to measure DNA damage induced by exposure to polycyclic aromatic hydrocarbons

Popis výsledku anglicky

The effect of exposure to polycyclic aromatic hydrocarbons (PAHs) to induce micronuclei (MN) measured using the lymphocytes cytokinesis-block micronucleus (CBMN) assay were evaluated in 34 studies according to the exposure: 20 studies in coke oven workers, 7 studies in different occupational exposures as alluminium industry workers, rubber factory workers, road construction workers, airport workers and diesel exposed workers, 6 studies on environmentaly exposed groups as police, volunteers and children. nnReviewed papers indicate that the CBMN assay is a sensitive biomarker of PAHs exposure in polluted air. Reviewed studies confirmed previous conclusions, that the frequency of MN measured using the lymphocyte CBMN is not significantly affected by smoking, females are more sensitive to PAHs than males, the frequency of MN is increased with age.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

—

Projekt

<a href="/cs/project/GA13-13458S" target="_blank" >GA13-13458S: Dopady znečištění ovzduší na genom novorozenců</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mutation Research-Reviews in Mutation Research

ISSN

1383-5742

e-ISSN

—

Svazek periodika

770

Číslo periodika v rámci svazku

oct - dec

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

162-169

Kód UT WoS článku

000390182300013

EID výsledku v databázi Scopus

2-s2.0-84995553624