Osteoblast Differentiation and Maturation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00491289" target="_blank" >RIV/68378041:_____/17:00491289 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Osteoblast Differentiation and Maturation

Popis výsledku v původním jazyce

The process of osteoblast differentiation and maturation is strictly regulated. During either endochondral or intramembrane ossification, mesenchymal stem cells condensate and differentiate into preosteoblasts and subsequently into osteoblasts. This differentiation is at all time points controlled by transcription factors, whose expression is under the influence of hormonal and growth factors. The function of transcription factors is the regulation of gene expression and to obtain the phenotype of osteoblasts. Activation and function of various types of factors during osteoblastic differentiation is managed by coordinated and complex processes. Knowledge of signaling pathways during osteogenic differentiation are used within the development and testing of scaffolds in bone tissue engineering.

Název v anglickém jazyce

Osteoblast Differentiation and Maturation

Popis výsledku anglicky

The process of osteoblast differentiation and maturation is strictly regulated. During either endochondral or intramembrane ossification, mesenchymal stem cells condensate and differentiate into preosteoblasts and subsequently into osteoblasts. This differentiation is at all time points controlled by transcription factors, whose expression is under the influence of hormonal and growth factors. The function of transcription factors is the regulation of gene expression and to obtain the phenotype of osteoblasts. Activation and function of various types of factors during osteoblastic differentiation is managed by coordinated and complex processes. Knowledge of signaling pathways during osteogenic differentiation are used within the development and testing of scaffolds in bone tissue engineering.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

10601 - Cell biology

Projekt

<a href="/cs/project/LO1309" target="_blank" >LO1309: Buněčná terapie a tkáňové náhrady</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Nanomaterials in Biomedical research

ISBN

978-80-906655-5-2

Počet stran výsledku

5

Strana od-do

56-60

Počet stran knihy

140

Název nakladatele

Proxima Tisk, s.r.o.

Místo vydání

Praha 3

Kód UT WoS kapitoly

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