Comparison of Phenotype and Secretory Functions of Mesenchymal Stem Cells Isolated from Patients Suffering from Amyotrophic Lateral Sclerosis and Healthy Donors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00491792" target="_blank" >RIV/68378041:_____/17:00491792 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of Phenotype and Secretory Functions of Mesenchymal Stem Cells Isolated from Patients Suffering from Amyotrophic Lateral Sclerosis and Healthy Donors

Popis výsledku v původním jazyce

Mesenchymal stem cells (MSCs) exert extensive differentiation potential and immunomodulatory properties. These properties make them a promising therapeutic tool providing several ways to improve prognosis and course of immedicable disorders such as amyotrophic lateral sclerosis (ALS). The choice between autologous and allogeneic MSC therapy is crucial, because there are studies demonstrating influence of ALS on properties of MSCs isolated from patients suffering from ALS. We tested both types of MSCs and conclude that we did not find any statistically significant differences in phenotype and production of selected soluble molecules between MSCs from healthy donors and patients suffering from ALS.

Název v anglickém jazyce

Comparison of Phenotype and Secretory Functions of Mesenchymal Stem Cells Isolated from Patients Suffering from Amyotrophic Lateral Sclerosis and Healthy Donors

Popis výsledku anglicky

Mesenchymal stem cells (MSCs) exert extensive differentiation potential and immunomodulatory properties. These properties make them a promising therapeutic tool providing several ways to improve prognosis and course of immedicable disorders such as amyotrophic lateral sclerosis (ALS). The choice between autologous and allogeneic MSC therapy is crucial, because there are studies demonstrating influence of ALS on properties of MSCs isolated from patients suffering from ALS. We tested both types of MSCs and conclude that we did not find any statistically significant differences in phenotype and production of selected soluble molecules between MSCs from healthy donors and patients suffering from ALS.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

10601 - Cell biology

Projekt

<a href="/cs/project/LO1309" target="_blank" >LO1309: Buněčná terapie a tkáňové náhrady</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Nanomaterials in Biomedical research

ISBN

978-80-906655-5-2

Počet stran výsledku

5

Strana od-do

96-100

Počet stran knihy

140

Název nakladatele

Proxima Tisk, s.r.o.

Místo vydání

Praha 3

Kód UT WoS kapitoly

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