Age-Related Changes in the Auditory Brainstem and Inferior Colliculus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F20%3A00539957" target="_blank" >RIV/68378041:_____/20:00539957 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/book/10.1007/978-3-030-49367-7" target="_blank" >https://link.springer.com/book/10.1007/978-3-030-49367-7</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Age-Related Changes in the Auditory Brainstem and Inferior Colliculus

Popis výsledku v původním jazyce

Aging is accompanied by specific changes in the processing of sound information that result from dysfunction of individual parts of the auditory system. Age-related changes in the function of the inner ear caused by pathologies occurring in the outer and inner hair cells (OHCs and IHCs), stria vascularis, and neurons of the spiral ganglion are transmitted to the central auditory system, where further pathological changes take place. The goal of this chapter is to describe aging-related changes that occur in the structure and function of the cochlear nuclei, nuclei of the superior olivary complex, and inferior colliculus. These changes inevitably influence the processing of acoustical information. Major pathological changes occurring in this part of the auditory system represent age-related losses of some specific types of neurons or their parts, particularly those connected with inhibitory functions. As a result of these losses, the processing of the fine temporal details of the acoustical signals appears to be impaired, particularly in the case of such complex signals as human speech. In addition, the brainstem and midbrain parts of the auditory system play important roles in the processing of space information and in the control of the intensity of the incoming acoustical signal by the olivocochlear bundle, both of these functions may be negatively influenced by aging. The effects of aging are described systematically as they appear in the structure, neurochemistry, and function of the brainstem and midbrain parts of the central auditory system.

Název v anglickém jazyce

Age-Related Changes in the Auditory Brainstem and Inferior Colliculus

Popis výsledku anglicky

Aging is accompanied by specific changes in the processing of sound information that result from dysfunction of individual parts of the auditory system. Age-related changes in the function of the inner ear caused by pathologies occurring in the outer and inner hair cells (OHCs and IHCs), stria vascularis, and neurons of the spiral ganglion are transmitted to the central auditory system, where further pathological changes take place. The goal of this chapter is to describe aging-related changes that occur in the structure and function of the cochlear nuclei, nuclei of the superior olivary complex, and inferior colliculus. These changes inevitably influence the processing of acoustical information. Major pathological changes occurring in this part of the auditory system represent age-related losses of some specific types of neurons or their parts, particularly those connected with inhibitory functions. As a result of these losses, the processing of the fine temporal details of the acoustical signals appears to be impaired, particularly in the case of such complex signals as human speech. In addition, the brainstem and midbrain parts of the auditory system play important roles in the processing of space information and in the control of the intensity of the incoming acoustical signal by the olivocochlear bundle, both of these functions may be negatively influenced by aging. The effects of aging are described systematically as they appear in the structure, neurochemistry, and function of the brainstem and midbrain parts of the central auditory system.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Aging and Hearing

ISBN

978-3-030-49366-0

Počet stran výsledku

30

Strana od-do

67-96

Počet stran knihy

323

Název nakladatele

Springer Nature Switzerland AG

Místo vydání

Cham

Kód UT WoS kapitoly

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