Head-shaking-induced nystagmus reflects dynamic vestibular compensation: A 2-year follow-up study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F22%3A00568786" target="_blank" >RIV/68378041:_____/22:00568786 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064173:_____/22:43924073 RIV/00216208:11120/22:43924073 RIV/00216208:11150/22:10448889 RIV/00179906:_____/22:10448889

Výsledek na webu

<a href="https://www.frontiersin.org/articles/10.3389/fneur.2022.949696/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fneur.2022.949696/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fneur.2022.949696" target="_blank" >10.3389/fneur.2022.949696</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Head-shaking-induced nystagmus reflects dynamic vestibular compensation: A 2-year follow-up study

Popis výsledku v původním jazyce

PurposeWe aimed to assess the ability of a head-shaking test (HST) to reflect vestibular compensation in patients after unilateral peripheral vestibular loss and to provide missing evidence and new insights into the features of head-shaking-induced nystagmus (HSN) over a 2-year follow-up. BackgroundHSN may occur after a prolonged sinusoidal oscillation of the head. HSN is frequently observed in subjects with vestibular function asymmetry, it usually beats toward the functionally intact or stronger ear and can be followed by a reversal of its direction. Study designA prospective observational case-control study. SettingsA tertiary academic referral center. MethodsA total of 38 patients after acute unilateral vestibular loss (22 patients with vestibular neuronitis and 16 patients after vestibular neurectomy) and 28 healthy controls were followed for four consecutive visits over a 2-year period. A complex vestibular assessment was performed on all participants, which included spontaneous nystagmus (SPN), the caloric test, the head-shaking test (HST), the video head impulse test (vHIT), the Timed Up and Go (TUG) test, and the Dizziness Handicap Inventory (DHI) questionnaire. We established the criteria for the poorly compensated group to assess different compensatory behaviors and results. ResultsWe found a time-related decrease in HSN (rho < -0.84, p < 0.001) after unilateral vestibular loss. After 2 years of follow-up, HSN intensity in compensated patients reached the level of the control group, TUG and DHI also improved to normal, however, the caloric and vHIT tests remained abnormal throughout all follow-ups, indicating a chronic vestibular deficit. Besides, poorly compensated patients had a well-detectable HSN throughout all follow-ups, TUG remained abnormal, and DHI showed at least a moderate deficit. ConclusionsOur study showed that, after a unilateral peripheral vestibular loss, the intensity of HSN decreased exponentially over time, reflecting an improvement in dynamic ability and self-perceived deficit. HSN tended to decline to the value of the control group once vestibular compensation was satisfactory and sufficient for a patient's everyday life. In contrast, well-detectable HSN in poorly compensated patients with insufficient clinical recovery confirmed the potential of HSN to reflect and distinguish between adequate and insufficient dynamic compensation. HSN could serve as an objective indicator of stable unilateral vestibular loss.

Název v anglickém jazyce

Head-shaking-induced nystagmus reflects dynamic vestibular compensation: A 2-year follow-up study

Popis výsledku anglicky

PurposeWe aimed to assess the ability of a head-shaking test (HST) to reflect vestibular compensation in patients after unilateral peripheral vestibular loss and to provide missing evidence and new insights into the features of head-shaking-induced nystagmus (HSN) over a 2-year follow-up. BackgroundHSN may occur after a prolonged sinusoidal oscillation of the head. HSN is frequently observed in subjects with vestibular function asymmetry, it usually beats toward the functionally intact or stronger ear and can be followed by a reversal of its direction. Study designA prospective observational case-control study. SettingsA tertiary academic referral center. MethodsA total of 38 patients after acute unilateral vestibular loss (22 patients with vestibular neuronitis and 16 patients after vestibular neurectomy) and 28 healthy controls were followed for four consecutive visits over a 2-year period. A complex vestibular assessment was performed on all participants, which included spontaneous nystagmus (SPN), the caloric test, the head-shaking test (HST), the video head impulse test (vHIT), the Timed Up and Go (TUG) test, and the Dizziness Handicap Inventory (DHI) questionnaire. We established the criteria for the poorly compensated group to assess different compensatory behaviors and results. ResultsWe found a time-related decrease in HSN (rho < -0.84, p < 0.001) after unilateral vestibular loss. After 2 years of follow-up, HSN intensity in compensated patients reached the level of the control group, TUG and DHI also improved to normal, however, the caloric and vHIT tests remained abnormal throughout all follow-ups, indicating a chronic vestibular deficit. Besides, poorly compensated patients had a well-detectable HSN throughout all follow-ups, TUG remained abnormal, and DHI showed at least a moderate deficit. ConclusionsOur study showed that, after a unilateral peripheral vestibular loss, the intensity of HSN decreased exponentially over time, reflecting an improvement in dynamic ability and self-perceived deficit. HSN tended to decline to the value of the control group once vestibular compensation was satisfactory and sufficient for a patient's everyday life. In contrast, well-detectable HSN in poorly compensated patients with insufficient clinical recovery confirmed the potential of HSN to reflect and distinguish between adequate and insufficient dynamic compensation. HSN could serve as an objective indicator of stable unilateral vestibular loss.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30206 - Otorhinolaryngology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Neurology

ISSN

1664-2295

e-ISSN

1664-2295

Svazek periodika

13

Číslo periodika v rámci svazku

sep.

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

11

Strana od-do

949696

Kód UT WoS článku

000870032600001

EID výsledku v databázi Scopus

2-s2.0-85139905712