Charakterizace chování samců myší odvozených z divokých zvířat

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F04%3A00105336" target="_blank" >RIV/68378050:_____/04:00105336 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Behavioural characterisation of wild derived male mice (Mus musculus musculus) of the PWD/Ph inbred strain

Popis výsledku v původním jazyce

There is a high degree of variation between PWD/Ph (Mus musculus musculus origin) and laboratory inbred mouse strains (principally Mus musculus domesticus origin). Now, a preliminary characterization of the behavior of PWD/Ph mice was performed. Groups of 10 PWD/Ph and C57BL/6J male mice were tested in the open field, novel object exploration task and Morris water maze. PWD/Ph were marginally more anxious than C57BL/6J mice in the open field but displayed much higher levels of exploration and lower anxiety than C57BL/6J mice following introduction of a novel object. PWD/Ph and C57BL/6J mice differed in their water escape training profiles in the Morris water maze. However, there were no differences in overall cognitive ability (spatial learning). Thisis the first quantification of the behavior of PWD/Ph mice and the results are promising for the potential of the consomic panel currently being generated with PWD/Ph and C57BL/6J as a tool for the molecular dissection of behavior

Název v anglickém jazyce

Behavioural characterisation of wild derived male mice (Mus musculus musculus) of the PWD/Ph inbred strain

Popis výsledku anglicky

There is a high degree of variation between PWD/Ph (Mus musculus musculus origin) and laboratory inbred mouse strains (principally Mus musculus domesticus origin). Now, a preliminary characterization of the behavior of PWD/Ph mice was performed. Groups of 10 PWD/Ph and C57BL/6J male mice were tested in the open field, novel object exploration task and Morris water maze. PWD/Ph were marginally more anxious than C57BL/6J mice in the open field but displayed much higher levels of exploration and lower anxiety than C57BL/6J mice following introduction of a novel object. PWD/Ph and C57BL/6J mice differed in their water escape training profiles in the Morris water maze. However, there were no differences in overall cognitive ability (spatial learning). Thisis the first quantification of the behavior of PWD/Ph mice and the results are promising for the potential of the consomic panel currently being generated with PWD/Ph and C57BL/6J as a tool for the molecular dissection of behavior

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Behavior Genetics

ISSN

0001-8244

e-ISSN

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Svazek periodika

34

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

621-630

Kód UT WoS článku

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EID výsledku v databázi Scopus

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