Canabis in the Development and Homeostasis of the Nerve System

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F13%3A00441188" target="_blank" >RIV/68378050:_____/13:00441188 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Canabis in the Development and Homeostasis of the Nerve System

Popis výsledku v původním jazyce

Marihuana is one of the most frequently abused illicit drugs among adolescents and young adults. As such, exposure to psychoactive ingredients, with delta 9-tetrahydrocanabinol (THC) being the most prevalent, collide with critical periods of brain development. Firstly, in mothers who cease to abuse cannabis at the onset of pregnancy, THC and other lipid-soluble substances might still circulate in their blood at levels that may interfere with the brain development of the fetus. This is due to the chemical nature of THC and related substances; these are lipophilic and accumulate in the body fat. During pregnancy, the fat redistribution leads to release of cannabinoids into the blood stream. These substances readily cross placental barrier and enter fetalcirculation. The second period of brain maturation that is influenced by THC exposure in many smokers is during puberty and is associated with an increased risk of neuropsychiatric consequences. The third negative aspect of cannabis abus

Název v anglickém jazyce

Canabis in the Development and Homeostasis of the Nerve System

Popis výsledku anglicky

Marihuana is one of the most frequently abused illicit drugs among adolescents and young adults. As such, exposure to psychoactive ingredients, with delta 9-tetrahydrocanabinol (THC) being the most prevalent, collide with critical periods of brain development. Firstly, in mothers who cease to abuse cannabis at the onset of pregnancy, THC and other lipid-soluble substances might still circulate in their blood at levels that may interfere with the brain development of the fetus. This is due to the chemical nature of THC and related substances; these are lipophilic and accumulate in the body fat. During pregnancy, the fat redistribution leads to release of cannabinoids into the blood stream. These substances readily cross placental barrier and enter fetalcirculation. The second period of brain maturation that is influenced by THC exposure in many smokers is during puberty and is associated with an increased risk of neuropsychiatric consequences. The third negative aspect of cannabis abus

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Česká a Slovenská neurologie a neurochirurgie

ISSN

1210-7859

e-ISSN

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Svazek periodika

76

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

559-564

Kód UT WoS článku

000331987000003

EID výsledku v databázi Scopus

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