Gene regulation in amphioxus: An insight from transgenic studies in amphioxus and vertebrates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F15%3A00455829" target="_blank" >RIV/68378050:_____/15:00455829 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.margen.2015.06.003" target="_blank" >http://dx.doi.org/10.1016/j.margen.2015.06.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.margen.2015.06.003" target="_blank" >10.1016/j.margen.2015.06.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Gene regulation in amphioxus: An insight from transgenic studies in amphioxus and vertebrates

Popis výsledku v původním jazyce

Cephalochordates, commonly known as amphioxus or lancelets, are the most basal subphylum of chordates. Cephalochordates are thus key to understanding the origin of vertebrates and molecular mechanisms underlying vertebrate evolution. The evolution of developmental control mechanisms during invertebrate-to-vertebrate transition involved not only gene duplication events, but also specific changes in spatial and temporal expression of many genes. To get insight into the spatiotemporal regulation of gene expression during invertebrate-to-vertebrate transition, functional studies of amphioxus gene regulatory elements are highly warranted. Here, we review transgenic studies performed in amphioxus and vertebrates using promoters and enhancers derived from thegenome of Branchiostoma floridae. We describe the current methods of transgenesis in amphioxus, provide evidence of ToI2 transposon-generated transgenic embryos of Branchiostoma lanceolatum and discuss possible future directions. We envi

Název v anglickém jazyce

Gene regulation in amphioxus: An insight from transgenic studies in amphioxus and vertebrates

Popis výsledku anglicky

Cephalochordates, commonly known as amphioxus or lancelets, are the most basal subphylum of chordates. Cephalochordates are thus key to understanding the origin of vertebrates and molecular mechanisms underlying vertebrate evolution. The evolution of developmental control mechanisms during invertebrate-to-vertebrate transition involved not only gene duplication events, but also specific changes in spatial and temporal expression of many genes. To get insight into the spatiotemporal regulation of gene expression during invertebrate-to-vertebrate transition, functional studies of amphioxus gene regulatory elements are highly warranted. Here, we review transgenic studies performed in amphioxus and vertebrates using promoters and enhancers derived from thegenome of Branchiostoma floridae. We describe the current methods of transgenesis in amphioxus, provide evidence of ToI2 transposon-generated transgenic embryos of Branchiostoma lanceolatum and discuss possible future directions. We envi

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

<a href="/cs/project/LO1419" target="_blank" >LO1419: Biomodely pro zdraví - Centrum modelových organismů</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Marine Genomics

ISSN

1874-7787

e-ISSN

—

Svazek periodika

24

Číslo periodika v rámci svazku

Dec

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

8

Strana od-do

159-166

Kód UT WoS článku

000367762200006

EID výsledku v databázi Scopus

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