CHICKEN DDNTFR23 AS A CANDIDATE RECEPTOR FOR AN ALV-F SUBGROUP
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F22%3A00567919" target="_blank" >RIV/68378050:_____/22:00567919 - isvavai.cz</a>
Výsledek na webu
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/37/67" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/37/67</a>
DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
CHICKEN DDNTFR23 AS A CANDIDATE RECEPTOR FOR AN ALV-F SUBGROUP
Popis výsledku v původním jazyce
Avian leukosis virus subgroups (ALV) A, B, C, D, E, J, and K are grouped according to their antigenic reactivity, superinfection interference, and cell receptor usage. However, these characteristics remain to be determined for the endogenous F subgroup. Therefore, we characterized the cell receptor usage for the F subgroup. We constructed arecombinant avian leukosis virus with the F subgroup envgene that replicates only in chicken cells. The F subgroup did not share the cell receptor usage with any other described ALV subgroup by the superinfection interference. We identifiedDDTNFR23 protein as the receptor in chicken and pheasant cells for the F subgroup by an infection of chicken/hamster radiation hybrids. Taken together, we provide amolecular characterization of the F subgroup avian leukosis virus and enhance our knowledge of receptor usage diversification within a closely related virus.
Název v anglickém jazyce
CHICKEN DDNTFR23 AS A CANDIDATE RECEPTOR FOR AN ALV-F SUBGROUP
Popis výsledku anglicky
Avian leukosis virus subgroups (ALV) A, B, C, D, E, J, and K are grouped according to their antigenic reactivity, superinfection interference, and cell receptor usage. However, these characteristics remain to be determined for the endogenous F subgroup. Therefore, we characterized the cell receptor usage for the F subgroup. We constructed arecombinant avian leukosis virus with the F subgroup envgene that replicates only in chicken cells. The F subgroup did not share the cell receptor usage with any other described ALV subgroup by the superinfection interference. We identifiedDDTNFR23 protein as the receptor in chicken and pheasant cells for the F subgroup by an infection of chicken/hamster radiation hybrids. Taken together, we provide amolecular characterization of the F subgroup avian leukosis virus and enhance our knowledge of receptor usage diversification within a closely related virus.
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
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OECD FORD obor
10607 - Virology
Návaznosti výsledku
Projekt
<a href="/cs/project/LX22NPO5103" target="_blank" >LX22NPO5103: Národní institut virologie a bakteriologie</a><br>
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů