A cytokinetic ring- driven cell rotation achieves Hertwig's rule in early development
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F24%3A00604431" target="_blank" >RIV/68378050:_____/24:00604431 - isvavai.cz</a>
Výsledek na webu
<a href="https://www.pnas.org/doi/10.1073/pnas.2318838121" target="_blank" >https://www.pnas.org/doi/10.1073/pnas.2318838121</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1073/pnas.2318838121" target="_blank" >10.1073/pnas.2318838121</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
A cytokinetic ring- driven cell rotation achieves Hertwig's rule in early development
Popis výsledku v původním jazyce
This discovery builds on earlier work from Sachs concerning orientations of subsequent cell divisions (3, 4) and is since known as Hertwig's long axis rule (5-12). Since the mitotic spindle is bisected during cell division for proper chromosome segregation, the axis along which the mitotic spindle is oriented determines the axis of cell division (13). Hence, the orientation of the mitotic spindle determines the axis along which a cell is divided. But how then does the mitotic spindle align with the long axis of a cell, thereby facilitating If misaligned, moving the spindle to orient it with the long axis of the cell requires force generation. What types of forces can act upon microtubules and microtubule asters? We distinguish force generation inside the cell, within the cytoplasm, from force generation at the cell cortex. First, within the cytoplasm, dynein motors that are attached to cytoSecond, microtubules that grow toward the periphery can continue to do so as they
Název v anglickém jazyce
A cytokinetic ring- driven cell rotation achieves Hertwig's rule in early development
Popis výsledku anglicky
This discovery builds on earlier work from Sachs concerning orientations of subsequent cell divisions (3, 4) and is since known as Hertwig's long axis rule (5-12). Since the mitotic spindle is bisected during cell division for proper chromosome segregation, the axis along which the mitotic spindle is oriented determines the axis of cell division (13). Hence, the orientation of the mitotic spindle determines the axis along which a cell is divided. But how then does the mitotic spindle align with the long axis of a cell, thereby facilitating If misaligned, moving the spindle to orient it with the long axis of the cell requires force generation. What types of forces can act upon microtubules and microtubule asters? We distinguish force generation inside the cell, within the cytoplasm, from force generation at the cell cortex. First, within the cytoplasm, dynein motors that are attached to cytoSecond, microtubules that grow toward the periphery can continue to do so as they
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10601 - Cell biology
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2024
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Proceedings of the National Academy of Sciences of the United States of America
ISSN
0027-8424
e-ISSN
1091-6490
Svazek periodika
121
Číslo periodika v rámci svazku
25
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
8
Strana od-do
10-10
Kód UT WoS článku
001318922600016
EID výsledku v databázi Scopus
2-s2.0-85196137911