Lipid-lncRNA Crossroads: An Overview of Interactions Between Lipids and lncRNA
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F25%3A00644721" target="_blank" >RIV/68378050:_____/25:00644721 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/00216208:11110/25:10500712
Výsledek na webu
<a href="https://www.mdpi.com/2073-4409/14/15/1193" target="_blank" >https://www.mdpi.com/2073-4409/14/15/1193</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/cells14151193" target="_blank" >10.3390/cells14151193</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Lipid-lncRNA Crossroads: An Overview of Interactions Between Lipids and lncRNA
Popis výsledku v původním jazyce
Long non-coding RNAs (lncRNAs) interact with a variety of biomolecules, including DNA, mRNAs, microRNA, and proteins, to regulate various cellular processes. Recently, their interactions with lipids have gained increasing attention as an emerging research area. Both lipids and lncRNAs play central roles in cellular regulation, and growing evidence reveals a complex interplay between these molecules. These interactions contribute to key biological functions, such as cancer progression, lipid droplet transport, autophagy, liquid-liquid phase separation, and the formation of organelles without membranes. Understanding the lipid-lncRNA interface opens new avenues for unraveling cellular regulation and disease mechanisms, holding great potential not only for elucidating the fundamental aspects of cellular biology but also for identifying innovative therapeutic targets for metabolic disorders and cancer. This review highlights the biological relevance of lipid-lncRNA interactions by exploring their roles in cellular organization, regulation, and diseases, including metabolic and cancer-related disorders.
Název v anglickém jazyce
Lipid-lncRNA Crossroads: An Overview of Interactions Between Lipids and lncRNA
Popis výsledku anglicky
Long non-coding RNAs (lncRNAs) interact with a variety of biomolecules, including DNA, mRNAs, microRNA, and proteins, to regulate various cellular processes. Recently, their interactions with lipids have gained increasing attention as an emerging research area. Both lipids and lncRNAs play central roles in cellular regulation, and growing evidence reveals a complex interplay between these molecules. These interactions contribute to key biological functions, such as cancer progression, lipid droplet transport, autophagy, liquid-liquid phase separation, and the formation of organelles without membranes. Understanding the lipid-lncRNA interface opens new avenues for unraveling cellular regulation and disease mechanisms, holding great potential not only for elucidating the fundamental aspects of cellular biology but also for identifying innovative therapeutic targets for metabolic disorders and cancer. This review highlights the biological relevance of lipid-lncRNA interactions by exploring their roles in cellular organization, regulation, and diseases, including metabolic and cancer-related disorders.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10601 - Cell biology
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2025
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Cells
ISSN
2073-4409
e-ISSN
2073-4409
Svazek periodika
14
Číslo periodika v rámci svazku
15
Stát vydavatele periodika
CH - Švýcarská konfederace
Počet stran výsledku
16
Strana od-do
1193
Kód UT WoS článku
001548687800001
EID výsledku v databázi Scopus
2-s2.0-105013319260