From membrane to skin: aqueous permeation control through light-responsive amphiphilic polymer co-networks

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F14%3A00438746" target="_blank" >RIV/68378271:_____/14:00438746 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/adfm.201400671" target="_blank" >http://dx.doi.org/10.1002/adfm.201400671</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/adfm.201400671" target="_blank" >10.1002/adfm.201400671</a>

Jazyk výsledku

angličtina

Název v původním jazyce

From membrane to skin: aqueous permeation control through light-responsive amphiphilic polymer co-networks

Popis výsledku v původním jazyce

The functionalization of amphiphilic polymer co-networks with lightresponsive spiropyran and spirooxazine derivatives leads to a new type of light-responsive materials. The material consisting of hydrophilic nanochannels shows desirable properties such as light-responsive permeability changes of aqueous caffeine solutions, an exceptional repeatability of the photochromism, and tunable basic permeability rates. The versatility of the system is demonstrated by using different functionalization routes suchas copolymerization of light-responsive monomers or crosslinker as well as postmodifi cation of the preformed amphiphilic network. Moreover, lightresponsive spirobenzopyran and novel spirooxazine derivatives are synthesized, which changes the propertiesof the light-responsive membranes after inclusion into the amphiphilic co-networks. Finally, the permeability of the delivery membrane can be tailored to match the properties of porcine skin, an in vitro model of human neonatal skin. One

Název v anglickém jazyce

From membrane to skin: aqueous permeation control through light-responsive amphiphilic polymer co-networks

Popis výsledku anglicky

The functionalization of amphiphilic polymer co-networks with lightresponsive spiropyran and spirooxazine derivatives leads to a new type of light-responsive materials. The material consisting of hydrophilic nanochannels shows desirable properties such as light-responsive permeability changes of aqueous caffeine solutions, an exceptional repeatability of the photochromism, and tunable basic permeability rates. The versatility of the system is demonstrated by using different functionalization routes suchas copolymerization of light-responsive monomers or crosslinker as well as postmodifi cation of the preformed amphiphilic network. Moreover, lightresponsive spirobenzopyran and novel spirooxazine derivatives are synthesized, which changes the propertiesof the light-responsive membranes after inclusion into the amphiphilic co-networks. Finally, the permeability of the delivery membrane can be tailored to match the properties of porcine skin, an in vitro model of human neonatal skin. One

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JI - Kompositní materiály

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Advanced Functional Materials

ISSN

1616-301X

e-ISSN

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Svazek periodika

24

Číslo periodika v rámci svazku

33

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

8

Strana od-do

5194-5201

Kód UT WoS článku

000341699200003

EID výsledku v databázi Scopus

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