Preparation of manganese perovskite magnetic nanoparticles and their mechanical treatment

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F14%3A00440955" target="_blank" >RIV/68378271:_____/14:00440955 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Preparation of manganese perovskite magnetic nanoparticles and their mechanical treatment

Popis výsledku v původním jazyce

Magnetic nanoparticles of manganese perovskite La1-xSrxMnO3 could find use in biomedical applications (MRI or MFH). These nanoparticles have several times higher relaxivity and higher heating efficiency than the commercial product based on iron oxide. Inaddition, heating the particles can be managed very well by appropriate setting of Curie temperature (Tc) which reduces the risk of overheating and damage of surrounding healthy tissue. For industrial production it is very important to prepare large quantities of these nanoparticles at once and optimize the process. Nowadays, we usually prepare about 50 g, which is ten times more than in laboratory scale. Our target is to improve current mechanical treatment of nanoparticles including rolling and milling after annealing and prepare larger amount of magnetic cores suitable for encapsulation by silica which can be applied in medicine. This is very problematic part of the process because yield after encapsulation is only about 20 %.

Název v anglickém jazyce

Preparation of manganese perovskite magnetic nanoparticles and their mechanical treatment

Popis výsledku anglicky

Magnetic nanoparticles of manganese perovskite La1-xSrxMnO3 could find use in biomedical applications (MRI or MFH). These nanoparticles have several times higher relaxivity and higher heating efficiency than the commercial product based on iron oxide. Inaddition, heating the particles can be managed very well by appropriate setting of Curie temperature (Tc) which reduces the risk of overheating and damage of surrounding healthy tissue. For industrial production it is very important to prepare large quantities of these nanoparticles at once and optimize the process. Nowadays, we usually prepare about 50 g, which is ten times more than in laboratory scale. Our target is to improve current mechanical treatment of nanoparticles including rolling and milling after annealing and prepare larger amount of magnetic cores suitable for encapsulation by silica which can be applied in medicine. This is very problematic part of the process because yield after encapsulation is only about 20 %.

Druh

O - Ostatní výsledky

CEP obor

BM - Fyzika pevných látek a magnetismus

OECD FORD obor

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Projekt

<a href="/cs/project/FR-TI3%2F521" target="_blank" >FR-TI3/521: Technologie přípravy nových magnetických nanočástic pro diagnostiku a terapii v onkologii</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů