Newsilver complexes with bioactive glycine and nicotinamide molecules – characterization, DNA binding, antimicrobial and anticancer evaluation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F17%3A00479608" target="_blank" >RIV/68378271:_____/17:00479608 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jinorgbio.2016.12.003" target="_blank" >http://dx.doi.org/10.1016/j.jinorgbio.2016.12.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jinorgbio.2016.12.003" target="_blank" >10.1016/j.jinorgbio.2016.12.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Newsilver complexes with bioactive glycine and nicotinamide molecules – characterization, DNA binding, antimicrobial and anticancer evaluation

Popis výsledku v původním jazyce

This study introduces a pair of newly synthesized silver complexes, [Ag2(HGly)2]n(NO3)2n (1) and [Ag(Nam)2]NO3•H2O (2) (Gly – glycine, Nam– nicotinamide), that were prepared and characterized by relevant methods in solid state (elemental, spectral, thermal and structural analysis) and their stability in solution was verified by 1H NMR measurements. Moreover, suitable reaction conditions were observed by potentiometry depending on pH in case of binary system Ag-Gly. The binding of the Ag(I) complexes to calf thymus DNA was investigated using electronic absorption, fluorescence and circular di chroism spectrophotometry.n

Název v anglickém jazyce

Newsilver complexes with bioactive glycine and nicotinamide molecules – characterization, DNA binding, antimicrobial and anticancer evaluation

Popis výsledku anglicky

This study introduces a pair of newly synthesized silver complexes, [Ag2(HGly)2]n(NO3)2n (1) and [Ag(Nam)2]NO3•H2O (2) (Gly – glycine, Nam– nicotinamide), that were prepared and characterized by relevant methods in solid state (elemental, spectral, thermal and structural analysis) and their stability in solution was verified by 1H NMR measurements. Moreover, suitable reaction conditions were observed by potentiometry depending on pH in case of binary system Ag-Gly. The binding of the Ag(I) complexes to calf thymus DNA was investigated using electronic absorption, fluorescence and circular di chroism spectrophotometry.n

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Inorganic Biochemistry

ISSN

0162-0134

e-ISSN

—

Svazek periodika

168

Číslo periodika v rámci svazku

Mar

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

12

Strana od-do

1-12

Kód UT WoS článku

000395498100001

EID výsledku v databázi Scopus

2-s2.0-85006279508