Hydrophilic luminescent silicon nanoparticles in steric colloidal solutions: their size, agglomeration and toxicity

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F17%3A00480901" target="_blank" >RIV/68378271:_____/17:00480901 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/17:10362733 RIV/00216208:11140/17:10362733 RIV/00216208:11320/17:10362733

Výsledek na webu

<a href="http://dx.doi.org/10.1002/pssc.201700195" target="_blank" >http://dx.doi.org/10.1002/pssc.201700195</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/pssc.201700195" target="_blank" >10.1002/pssc.201700195</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Hydrophilic luminescent silicon nanoparticles in steric colloidal solutions: their size, agglomeration and toxicity

Popis výsledku v původním jazyce

Luminescent silicon nanoparticles are promising for in-tracellular biological research as luminescent probe for in vitro and in vivo studies. We prepared nanoclusters of hydrophilic highly porous silicon by electrochemical etching. Colloidal suspensions of the nanoparticles in steric organics (bovine serum albumin (BSA), glutamic acid, dextran and glycine) were prepared to attempt to stabilize the nanoparticles and prevent their further agglomeration. The zeta potential indicates good stability for BSA and glycine solutions, while the zeta potentials of water, dextran and glutamic acid show that nanoparticles tend to agglomerate. Strong orange luminescence of nanoparticles is situated between 600 and 700 nm and remains stable in all used organic colloidal solutions. Performed study of in vitro toxicity revealed that sterically stabilized silicon nanoparticles are cytotoxic only at the highest used concentration (500 µg/ml) of the silicon nanoparticles in water and BSA.n

Název v anglickém jazyce

Hydrophilic luminescent silicon nanoparticles in steric colloidal solutions: their size, agglomeration and toxicity

Popis výsledku anglicky

Luminescent silicon nanoparticles are promising for in-tracellular biological research as luminescent probe for in vitro and in vivo studies. We prepared nanoclusters of hydrophilic highly porous silicon by electrochemical etching. Colloidal suspensions of the nanoparticles in steric organics (bovine serum albumin (BSA), glutamic acid, dextran and glycine) were prepared to attempt to stabilize the nanoparticles and prevent their further agglomeration. The zeta potential indicates good stability for BSA and glycine solutions, while the zeta potentials of water, dextran and glutamic acid show that nanoparticles tend to agglomerate. Strong orange luminescence of nanoparticles is situated between 600 and 700 nm and remains stable in all used organic colloidal solutions. Performed study of in vitro toxicity revealed that sterically stabilized silicon nanoparticles are cytotoxic only at the highest used concentration (500 µg/ml) of the silicon nanoparticles in water and BSA.n

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

10610 - Biophysics

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physica Status Solidi C: Current Topics in Solid State Physics

ISSN

1862-6351

e-ISSN

—

Svazek periodika

14

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

4

Strana od-do

—

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85029208585