Chiral separation of novel diazenes on a polysaccharide-basedstationary phase in the reversed-phase mode

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F17%3A00483337" target="_blank" >RIV/68378271:_____/17:00483337 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22340/17:43903865

Výsledek na webu

<a href="http://dx.doi.org/10.1002/jssc.201601386" target="_blank" >http://dx.doi.org/10.1002/jssc.201601386</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.201601386" target="_blank" >10.1002/jssc.201601386</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chiral separation of novel diazenes on a polysaccharide-basedstationary phase in the reversed-phase mode

Popis výsledku v původním jazyce

Chiral HPLC separation of two recently synthesized liquid crystalline materials C1 and C2 was studied in the reversed-phase mode. Both materials have an azo-moiety and one chiral center in their molecular structures. The compounds were analyzed in both of their possible forms, the more thermodynamically stable E form and the labile Z form. The conditions and time scale of the UV-induced E toZ transition were briefly evaluated. Under the optimized conditions, we were able to baseline separate S and R enantiomers of both of the studied materials not only in their E forms, but also in their Z forms. In comparison to the separation in the normal-phase mode, which we have reported recently, the resolution in the reversed-phase mode is significantly better. Interestingly, peak reversal was noticed for the S and R enantiomers when the separation was carried out with E versus Z forms of both compounds.n

Název v anglickém jazyce

Chiral separation of novel diazenes on a polysaccharide-basedstationary phase in the reversed-phase mode

Popis výsledku anglicky

Chiral HPLC separation of two recently synthesized liquid crystalline materials C1 and C2 was studied in the reversed-phase mode. Both materials have an azo-moiety and one chiral center in their molecular structures. The compounds were analyzed in both of their possible forms, the more thermodynamically stable E form and the labile Z form. The conditions and time scale of the UV-induced E toZ transition were briefly evaluated. Under the optimized conditions, we were able to baseline separate S and R enantiomers of both of the studied materials not only in their E forms, but also in their Z forms. In comparison to the separation in the normal-phase mode, which we have reported recently, the resolution in the reversed-phase mode is significantly better. Interestingly, peak reversal was noticed for the S and R enantiomers when the separation was carried out with E versus Z forms of both compounds.n

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GA15-02843S" target="_blank" >GA15-02843S: Hybridní a kompozitní systémy založené na mesogenních látkách a nanočásticích</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Separation Science

ISSN

1615-9306

e-ISSN

—

Svazek periodika

40

Číslo periodika v rámci svazku

7

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

1465-1469

Kód UT WoS článku

000399782900004

EID výsledku v databázi Scopus

2-s2.0-85016956613