Warburg effect—damping of electromagnetic oscillations

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F17%3A00483569" target="_blank" >RIV/68378271:_____/17:00483569 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1080/15368378.2017.1326933" target="_blank" >http://dx.doi.org/10.1080/15368378.2017.1326933</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/15368378.2017.1326933" target="_blank" >10.1080/15368378.2017.1326933</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Warburg effect—damping of electromagnetic oscillations

Popis výsledku v původním jazyce

Mitochondrial dysfunction is a central defect in cells creating the Warburg and reverse Warburg effect cancers. Lowering of the inner membrane potential and shifting of the working point of mitochondria to high values of pH causes reorganization of the ordered water layer at the mitochondrial membrane. The reorganized ordered water layers at high pH values release electrons which are transferred to the cytosol rim of the layer. The electrons damp electromagnetic activity of Warburg effect cancer cells or fibroblasts associated with reverse Warburg effect cancer cells leading to lowered electromagnetic activity, disturbed coherence, increased oscillation frequencies and decreased level of biological functions. In reverse Warburg effect cancers, associated fibroblasts supply energy-rich metabolites to the cancer cell resulting in increased power of electromagnetic field, fluctuations due to shift of oscillations to an unstable nonlinear region, decreased frequency and loss of coherence.n

Název v anglickém jazyce

Warburg effect—damping of electromagnetic oscillations

Popis výsledku anglicky

Mitochondrial dysfunction is a central defect in cells creating the Warburg and reverse Warburg effect cancers. Lowering of the inner membrane potential and shifting of the working point of mitochondria to high values of pH causes reorganization of the ordered water layer at the mitochondrial membrane. The reorganized ordered water layers at high pH values release electrons which are transferred to the cytosol rim of the layer. The electrons damp electromagnetic activity of Warburg effect cancer cells or fibroblasts associated with reverse Warburg effect cancer cells leading to lowered electromagnetic activity, disturbed coherence, increased oscillation frequencies and decreased level of biological functions. In reverse Warburg effect cancers, associated fibroblasts supply energy-rich metabolites to the cancer cell resulting in increased power of electromagnetic field, fluctuations due to shift of oscillations to an unstable nonlinear region, decreased frequency and loss of coherence.n

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10610 - Biophysics

Projekt

<a href="/cs/project/GA16-12757S" target="_blank" >GA16-12757S: Feroelektrické vlastnosti biologických struktur</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electromagnetic Biology and Medicine

ISSN

1536-8378

e-ISSN

—

Svazek periodika

36

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

270-278

Kód UT WoS článku

000411461500006

EID výsledku v databázi Scopus

2-s2.0-85020223825