Magnetic oxide particles with gold nanoshells: synthesis, properties and cytotoxic effects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F17%3A00493346" target="_blank" >RIV/68378271:_____/17:00493346 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216275:25310/17:39910659 RIV/60461373:22340/17:43903063

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.colsurfa.2017.02.052" target="_blank" >http://dx.doi.org/10.1016/j.colsurfa.2017.02.052</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colsurfa.2017.02.052" target="_blank" >10.1016/j.colsurfa.2017.02.052</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Magnetic oxide particles with gold nanoshells: synthesis, properties and cytotoxic effects

Popis výsledku v původním jazyce

A successful synthesis and detailed study of complex Mn-Zn ferrite core-shell nanoparticles, whose shell is composed of primary silica layer and secondary gold coating, are presented. Magnetic cores Mn0.61Zn0.42Fe1.98O4 are synthesized as a single-phase product by hydrothermal procedure. The cores are embedded in amorphous silica, and gold shell is formed on their surface by a seed-and-growth synthesis. EDS, ICP-MS, and magnetometry provide coherent results on the chemical composition. Colloidal stability of the complex particles in water is evidenced by DLS. 4-mercaptobenzoic acid and 7-mercapto-4-methylcoumarin are covalently attached to the surface of the particles. Both the molecules provide strong SERS signals, and the particles modified with the coumarin derivate constitute an efficient label for fluorescence microscopy. Finally, biological study on two different cell lines is carried out, dealing with the viability and real-time monitoring of proliferation and adhesion of cells.n

Název v anglickém jazyce

Magnetic oxide particles with gold nanoshells: synthesis, properties and cytotoxic effects

Popis výsledku anglicky

A successful synthesis and detailed study of complex Mn-Zn ferrite core-shell nanoparticles, whose shell is composed of primary silica layer and secondary gold coating, are presented. Magnetic cores Mn0.61Zn0.42Fe1.98O4 are synthesized as a single-phase product by hydrothermal procedure. The cores are embedded in amorphous silica, and gold shell is formed on their surface by a seed-and-growth synthesis. EDS, ICP-MS, and magnetometry provide coherent results on the chemical composition. Colloidal stability of the complex particles in water is evidenced by DLS. 4-mercaptobenzoic acid and 7-mercapto-4-methylcoumarin are covalently attached to the surface of the particles. Both the molecules provide strong SERS signals, and the particles modified with the coumarin derivate constitute an efficient label for fluorescence microscopy. Finally, biological study on two different cell lines is carried out, dealing with the viability and real-time monitoring of proliferation and adhesion of cells.n

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Projekt

<a href="/cs/project/GA16-04340S" target="_blank" >GA16-04340S: Oxidové nanomagnety, jejich vlastnosti a interakce s biologickými systémy</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Colloids and Surfaces. A - Physicochemical and Engineering Aspects

ISSN

0927-7757

e-ISSN

—

Svazek periodika

520

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

922-932

Kód UT WoS článku

000401401100103

EID výsledku v databázi Scopus

2-s2.0-85014394602