Matrices of ferromagnetic microwires for the control of cellular dynamics and localized delivery of medicines

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00521437" target="_blank" >RIV/68378271:_____/19:00521437 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1134/s0031918x19060036" target="_blank" >https://doi.org/10.1134/s0031918x19060036</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1134/S0031918X19060036" target="_blank" >10.1134/S0031918X19060036</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Matrices of ferromagnetic microwires for the control of cellular dynamics and localized delivery of medicines

Popis výsledku v původním jazyce

A microwire in a biocompatible shell can be introduced into soft tissues or into blood vessels to maintain the biofunctioning of magnetic nanoparticles or stem cells with magnetic markers circulating in the blood. The magnetic fields created by the lattices of microwires are characterized by strong spatial gradients and can change over time in a specified manner. Such fields are necessary for the development of various magnetophoretic analytical chips for controlling the kinetics of cells and also for controlled drug delivery. A system of diametrically magnetized microwires is suggested in this paper, which possesses an energy minimum necessary for the stable capture of diamagnetic cells. The suggested dipole system is also promising for the accelerated diffusion transfer of magnetic nanoparticles, which are located in a liquid carrier, due to a gradient magnetic field.

Název v anglickém jazyce

Matrices of ferromagnetic microwires for the control of cellular dynamics and localized delivery of medicines

Popis výsledku anglicky

A microwire in a biocompatible shell can be introduced into soft tissues or into blood vessels to maintain the biofunctioning of magnetic nanoparticles or stem cells with magnetic markers circulating in the blood. The magnetic fields created by the lattices of microwires are characterized by strong spatial gradients and can change over time in a specified manner. Such fields are necessary for the development of various magnetophoretic analytical chips for controlling the kinetics of cells and also for controlled drug delivery. A system of diametrically magnetized microwires is suggested in this paper, which possesses an energy minimum necessary for the stable capture of diamagnetic cells. The suggested dipole system is also promising for the accelerated diffusion transfer of magnetic nanoparticles, which are located in a liquid carrier, due to a gradient magnetic field.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Projekt

<a href="/cs/project/EF16_019%2F0000760" target="_blank" >EF16_019/0000760: Fyzika pevných látek pro 21. století</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physics of Metals and Metallography

ISSN

0031-918X

e-ISSN

—

Svazek periodika

120

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

RU - Ruská federace

Počet stran výsledku

7

Strana od-do

556-562

Kód UT WoS článku

000473521800003

EID výsledku v databázi Scopus

2-s2.0-85068553860