Effective control of optical purity by chiral HPLC separation for ester-based liquid crystalline materials forming anticlinic smectic phases

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F21%3A00541667" target="_blank" >RIV/68378271:_____/21:00541667 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/21:10424447

Výsledek na webu

<a href="https://doi.org/10.1080/02678292.2020.1762937" target="_blank" >https://doi.org/10.1080/02678292.2020.1762937</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/02678292.2020.1762937" target="_blank" >10.1080/02678292.2020.1762937</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effective control of optical purity by chiral HPLC separation for ester-based liquid crystalline materials forming anticlinic smectic phases

Popis výsledku v původním jazyce

Effective control of optical purity by chiral separation of (S) and (R) enantiomers remains an actual and highlighted task while designing new chiral organic materials. An efficient methodology to solve this task has been developed and verified on a specifically designed series of chiral fluorinated liquid-crystalline materials with lateral substitution on the molecular core. HPLC was done using amylose based stationary phases. The self-assembling behaviour of new racemic materials was established. While establishing the chiral separation behaviour, the optimal separation conditions were taken over from our previous study and used for two chiral columns with coated amylose as chiral selector. Interestingly, two racemic materials demonstrated an unexpected change in enantiomer elution order. This is a very important information from separation point of view, e.g. preparative chiral chromatography.

Název v anglickém jazyce

Effective control of optical purity by chiral HPLC separation for ester-based liquid crystalline materials forming anticlinic smectic phases

Popis výsledku anglicky

Effective control of optical purity by chiral separation of (S) and (R) enantiomers remains an actual and highlighted task while designing new chiral organic materials. An efficient methodology to solve this task has been developed and verified on a specifically designed series of chiral fluorinated liquid-crystalline materials with lateral substitution on the molecular core. HPLC was done using amylose based stationary phases. The self-assembling behaviour of new racemic materials was established. While establishing the chiral separation behaviour, the optimal separation conditions were taken over from our previous study and used for two chiral columns with coated amylose as chiral selector. Interestingly, two racemic materials demonstrated an unexpected change in enantiomer elution order. This is a very important information from separation point of view, e.g. preparative chiral chromatography.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10401 - Organic chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Liquid Crystals

ISSN

0267-8292

e-ISSN

1366-5855

Svazek periodika

48

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

43-53

Kód UT WoS článku

000551613100001

EID výsledku v databázi Scopus

2-s2.0-85088541457