Hydrogel Scaffolds Contribute to the Osteogenesis and Chondrogenesis in the Small Osteochondral Defects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21110%2F11%3A00189925" target="_blank" >RIV/68407700:21110/11:00189925 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.intechopen.com/articles/show/title/hydrogel-scaffolds-contribute-to-the-osteogenesis-and-chondrogenesis-in-the-small-osteochongral-defe" target="_blank" >http://www.intechopen.com/articles/show/title/hydrogel-scaffolds-contribute-to-the-osteogenesis-and-chondrogenesis-in-the-small-osteochongral-defe</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Hydrogel Scaffolds Contribute to the Osteogenesis and Chondrogenesis in the Small Osteochondral Defects

Popis výsledku v původním jazyce

Many people are stricken with degenerative osteochondral defects. osteochondral defects. Modern therapies of osteochondral defects are focused (for example) on the transplantation of osteochondral autografts, rushed spongiosa with collagen, chondrocytesand many others. The insertion of a crushed autologous bone graft has been reported as a possible therapy. However, the regenerative biomechanical (material) quality was less than 70% of healthy cartilage for fragments and controls. The transplantation of autologous osteochondral 3D-cylinders is one of several surgical therapies. During operations osteochondral defects are filled with material of a natural histological structure. However, the subchondral bone plates are interrupted and the biomechanicalstability between the original tissue and the transplanted tissue is different. The biophysical and biochemical fixation of replacements and/or scaffolds to the tissue depends dominantly: (a) on the biomechanical properties and biochemic

Název v anglickém jazyce

Hydrogel Scaffolds Contribute to the Osteogenesis and Chondrogenesis in the Small Osteochondral Defects

Popis výsledku anglicky

Many people are stricken with degenerative osteochondral defects. osteochondral defects. Modern therapies of osteochondral defects are focused (for example) on the transplantation of osteochondral autografts, rushed spongiosa with collagen, chondrocytesand many others. The insertion of a crushed autologous bone graft has been reported as a possible therapy. However, the regenerative biomechanical (material) quality was less than 70% of healthy cartilage for fragments and controls. The transplantation of autologous osteochondral 3D-cylinders is one of several surgical therapies. During operations osteochondral defects are filled with material of a natural histological structure. However, the subchondral bone plates are interrupted and the biomechanicalstability between the original tissue and the transplanted tissue is different. The biophysical and biochemical fixation of replacements and/or scaffolds to the tissue depends dominantly: (a) on the biomechanical properties and biochemic

Druh

C - Kapitola v odborné knize

CEP obor

FI - Traumatologie a ortopedie

OECD FORD obor

—

Projekt

<a href="/cs/project/GA106%2F06%2F0761" target="_blank" >GA106/06/0761: Hybridní biokompozit nové generace</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Biomaterials Applications for Nanomedicine

ISBN

978-953-307-661-4

Počet stran výsledku

16

Strana od-do

53-68

Počet stran knihy

458

Název nakladatele

InTech

Místo vydání

Rijeka

Kód UT WoS kapitoly

—