Electronic distraction fixation apparatus stimulates new bone formation in callus

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21110%2F14%3A00216533" target="_blank" >RIV/68407700:21110/14:00216533 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21230/14:00216533 RIV/68407700:21220/14:00216533

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Electronic distraction fixation apparatus stimulates new bone formation in callus

Popis výsledku v původním jazyce

Biomechanical loading affects bone structures. The anabolic effects of cyclic biomechanical loading on bone tissue are influenced by the frequency of loading. Mechanotransduction appears to involve a complex interaction between extracellular fluid shearforces and cellular mechanics. Bone cells are activated by both the cyclic fluid shear stresses and transported ions/molecules in fluid flow. The cyclic loading stimulates new bone formation through (for example) integrin linkages and ion channels. Cyclic stress/strain changes in bone and the cyclic fluid flow in intercellular networks can be induced by the dynamic electronic fixative (EDF). The dynamic effects of EDF stimulate the distraction osteogenesis (desmogenesis). Increasing the rate or frequency by which dynamic loading is applied greatly improves bone tissue mechanosensitivity, possibly due to loading-induced extracellular fluid forces around bone cells, that serve as mechanosensors. The elongation of long bones by EDF is acco

Název v anglickém jazyce

Electronic distraction fixation apparatus stimulates new bone formation in callus

Popis výsledku anglicky

Biomechanical loading affects bone structures. The anabolic effects of cyclic biomechanical loading on bone tissue are influenced by the frequency of loading. Mechanotransduction appears to involve a complex interaction between extracellular fluid shearforces and cellular mechanics. Bone cells are activated by both the cyclic fluid shear stresses and transported ions/molecules in fluid flow. The cyclic loading stimulates new bone formation through (for example) integrin linkages and ion channels. Cyclic stress/strain changes in bone and the cyclic fluid flow in intercellular networks can be induced by the dynamic electronic fixative (EDF). The dynamic effects of EDF stimulate the distraction osteogenesis (desmogenesis). Increasing the rate or frequency by which dynamic loading is applied greatly improves bone tissue mechanosensitivity, possibly due to loading-induced extracellular fluid forces around bone cells, that serve as mechanosensors. The elongation of long bones by EDF is acco

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FI - Traumatologie a ortopedie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Pohybové ústrojí. Pokroky ve výzkumu, diagnostice a terapii

ISSN

1212-4575

e-ISSN

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Svazek periodika

21

Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

3

Strana od-do

28-30

Kód UT WoS článku

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EID výsledku v databázi Scopus

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