Relay Feedback Oscillator Design for Modeling Circadian Rhythms in Cyanobacteria

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F11%3A00194392" target="_blank" >RIV/68407700:21220/11:00194392 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/86652079:_____/12:00482418

Výsledek na webu

<a href="http://dx.doi.org/10.1115/IMECE2011-64996" target="_blank" >http://dx.doi.org/10.1115/IMECE2011-64996</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1115/IMECE2011-64996" target="_blank" >10.1115/IMECE2011-64996</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Relay Feedback Oscillator Design for Modeling Circadian Rhythms in Cyanobacteria

Popis výsledku v původním jazyce

The paper introduces a relay feedback oscillator for modeling circadian rhythms in cyanobacteria. The relay feedback oscillator is equipped with low pass filter F(j?), hysteresis-type relay and negative feedback. This negative feedback represents an autoregulatory mechanism of the circadian clock and the notion of this autoregulatory mechanism is based on the well-known Goodwin biochemical oscillator [1]. The relay is responsible for the mediation of both the activation and degradation of oscillator state variables (protein concentrations) and in this way the pacemaker is constituted. Later on, low pass filter poles are identified for the purpose of modeling auto-oscillations with the free running period of 24h and the method of the pole identificationconsists in an ultimate frequency test providing stability margin of a single-loop composed of the filter and the relay in the feedback. Next, a relay output / input ratio of amplitudes and hysteresis are found out by the graphical test

Název v anglickém jazyce

Relay Feedback Oscillator Design for Modeling Circadian Rhythms in Cyanobacteria

Popis výsledku anglicky

The paper introduces a relay feedback oscillator for modeling circadian rhythms in cyanobacteria. The relay feedback oscillator is equipped with low pass filter F(j?), hysteresis-type relay and negative feedback. This negative feedback represents an autoregulatory mechanism of the circadian clock and the notion of this autoregulatory mechanism is based on the well-known Goodwin biochemical oscillator [1]. The relay is responsible for the mediation of both the activation and degradation of oscillator state variables (protein concentrations) and in this way the pacemaker is constituted. Later on, low pass filter poles are identified for the purpose of modeling auto-oscillations with the free running period of 24h and the method of the pole identificationconsists in an ultimate frequency test providing stability margin of a single-loop composed of the filter and the relay in the feedback. Next, a relay output / input ratio of amplitudes and hysteresis are found out by the graphical test

Druh

D - Stať ve sborníku

CEP obor

BC - Teorie a systémy řízení

OECD FORD obor

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Projekt

<a href="/cs/project/1M0567" target="_blank" >1M0567: Centrum aplikované kybernetiky</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

ASME 2011 International Mechanical Engineering Congress and Exposition (IMECE2011)

ISBN

978-0-7918-5488-4

ISSN

—

e-ISSN

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Počet stran výsledku

8

Strana od-do

549-556

Název nakladatele

American Society of Mechanical Engineers - ASME

Místo vydání

New York

Místo konání akce

Denver, CO

Datum konání akce

11. 11. 2011

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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