Nanoindentation of Intervertebral Disc Tissues Localized by SHG Imaging

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F12%3A00193032" target="_blank" >RIV/68407700:21220/12:00193032 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1080/10255842.2012.713601" target="_blank" >http://dx.doi.org/10.1080/10255842.2012.713601</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/10255842.2012.713601" target="_blank" >10.1080/10255842.2012.713601</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nanoindentation of Intervertebral Disc Tissues Localized by SHG Imaging

Popis výsledku v původním jazyce

The research on mechanical properties of cartilaginous endplate seems to be more and more actual at present. Endplate is a layer of hyaline cartilage between the intervertebral disc (IVD) and vertebral body. The calcification of the endplate causes restriction of the IVD nutrition and its failure afterwards [1]. Degeneration processes influence the mechanical properties of tissue, which we are going to examine. The information on local mechanical properties of tissues could also serve as qualitative parameters of well-cultured tissue by tissue engineers. Because of small size of native endplate (thickness<1mm), the instrumented nanoindentation is considerable technique for this task. Especially, mode of nanoscale dynamic mechanical analysis (nanoDMA) was designed for viscoelastic materials testing.This paper presents localization of cartilaginous endplate by Second Harmonic Generation (SHG) imaging in combination with nanoindentation.

Název v anglickém jazyce

Nanoindentation of Intervertebral Disc Tissues Localized by SHG Imaging

Popis výsledku anglicky

The research on mechanical properties of cartilaginous endplate seems to be more and more actual at present. Endplate is a layer of hyaline cartilage between the intervertebral disc (IVD) and vertebral body. The calcification of the endplate causes restriction of the IVD nutrition and its failure afterwards [1]. Degeneration processes influence the mechanical properties of tissue, which we are going to examine. The information on local mechanical properties of tissues could also serve as qualitative parameters of well-cultured tissue by tissue engineers. Because of small size of native endplate (thickness<1mm), the instrumented nanoindentation is considerable technique for this task. Especially, mode of nanoscale dynamic mechanical analysis (nanoDMA) was designed for viscoelastic materials testing.This paper presents localization of cartilaginous endplate by Second Harmonic Generation (SHG) imaging in combination with nanoindentation.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

—

Projekt

<a href="/cs/project/TA01010185" target="_blank" >TA01010185: Nové materiály a povrchové vrstvy pro bionický návrh kloubních náhrad</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Computer Methods in Biomechanics and Biomedical Engineering

ISSN

1025-5842

e-ISSN

—

Svazek periodika

15

Číslo periodika v rámci svazku

S

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

2

Strana od-do

335-336

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—