Biomechanics of nanoparticles self - assembly in lipid bilayer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F14%3A00224598" target="_blank" >RIV/68407700:21220/14:00224598 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.zcu.cz/pracoviste/vyd/online/Humanic_web.pdf" target="_blank" >http://www.zcu.cz/pracoviste/vyd/online/Humanic_web.pdf</a>

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Biomechanics of nanoparticles self - assembly in lipid bilayer

Popis výsledku v původním jazyce

Nanoparticles aggregation in lipid bilayer depends on the method of preparation: forming distributed monolayer if prepared by extrusion process or forming hybrid vesicles with nanoparticles segregated into hemispherical domains if prepared by dialysis. The aim of the study was to explain two forms of nanoparticles configuration by assuming changes in biomembrane bending and stretching energy. Monte Carlo simulation of membrane mechanics shows that an energetical barrier exists between condensed and distributed configuration of membrane particles. We propose that two distinct forms of nanoparticles configuration corresponds to two energetically stable states.

Název v anglickém jazyce

Biomechanics of nanoparticles self - assembly in lipid bilayer

Popis výsledku anglicky

Nanoparticles aggregation in lipid bilayer depends on the method of preparation: forming distributed monolayer if prepared by extrusion process or forming hybrid vesicles with nanoparticles segregated into hemispherical domains if prepared by dialysis. The aim of the study was to explain two forms of nanoparticles configuration by assuming changes in biomembrane bending and stretching energy. Monte Carlo simulation of membrane mechanics shows that an energetical barrier exists between condensed and distributed configuration of membrane particles. We propose that two distinct forms of nanoparticles configuration corresponds to two energetically stable states.

Druh

O - Ostatní výsledky

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů