Electroactive Films on Titanium Alloys as Bioactive Coatings for Hard Tissue Replacement

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F16%3A00242827" target="_blank" >RIV/68407700:21220/16:00242827 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Electroactive Films on Titanium Alloys as Bioactive Coatings for Hard Tissue Replacement

Popis výsledku v původním jazyce

Surface biocompatibility has been intensively studied in connection with medical implants. Various factors like surface wettability, roughness or chemical composition have been found to influence the biocompatibility. We focused our attention on studying coatings prepared from an electrically bioactive material (i.e. a ferroelectric influencing the adhesion, growth and differentiation of osteogenic cells) as a new trend for hard tissue replacement. TiNb is high corrosion resistant and nontoxic material potentially applicable as a support for these ferrolectric coatings. In the first step, we investigated TiNb coatings deposited by magnetron sputtering on substrates made from Ti, Ti alloys Ti39Nb and Ti6Al4V and stainless steel. Optimal conditions for deposition of chemically stable and biocompatible coatings were found. Significant layer properties as crystalline structure, chemical composition, roughness, etc. were characterized. It was found that the layer properties substantially depend on the substrate type. In the next step, the TiNb coatings was covered using a method described elsewhere by a spontaneously polarized ferroelectric film (BaTiO3, LiNbO3) with an electric charge on the surface. Growth of the human osteogenic cells was used as the surface biocompatibility test. Biocompatibility of the surfaces prepared by these two methods were compared.

Název v anglickém jazyce

Electroactive Films on Titanium Alloys as Bioactive Coatings for Hard Tissue Replacement

Popis výsledku anglicky

Surface biocompatibility has been intensively studied in connection with medical implants. Various factors like surface wettability, roughness or chemical composition have been found to influence the biocompatibility. We focused our attention on studying coatings prepared from an electrically bioactive material (i.e. a ferroelectric influencing the adhesion, growth and differentiation of osteogenic cells) as a new trend for hard tissue replacement. TiNb is high corrosion resistant and nontoxic material potentially applicable as a support for these ferrolectric coatings. In the first step, we investigated TiNb coatings deposited by magnetron sputtering on substrates made from Ti, Ti alloys Ti39Nb and Ti6Al4V and stainless steel. Optimal conditions for deposition of chemically stable and biocompatible coatings were found. Significant layer properties as crystalline structure, chemical composition, roughness, etc. were characterized. It was found that the layer properties substantially depend on the substrate type. In the next step, the TiNb coatings was covered using a method described elsewhere by a spontaneously polarized ferroelectric film (BaTiO3, LiNbO3) with an electric charge on the surface. Growth of the human osteogenic cells was used as the surface biocompatibility test. Biocompatibility of the surfaces prepared by these two methods were compared.

Druh

O - Ostatní výsledky

CEP obor

JK - Koroze a povrchové úpravy materiálu

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů