Electrospun collagen variability characterized by tensile testing

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F20%3A00336818" target="_blank" >RIV/68407700:21220/20:00336818 - isvavai.cz</a>

Výsledek na webu

<a href="https://link.springer.com/chapter/10.1007/978-3-030-31635-8_150" target="_blank" >https://link.springer.com/chapter/10.1007/978-3-030-31635-8_150</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-030-31635-8_150" target="_blank" >10.1007/978-3-030-31635-8_150</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electrospun collagen variability characterized by tensile testing

Popis výsledku v původním jazyce

The objective of this study was to verify repeatability of the preparation process of the collagen nanofibrous layers. The layers were fabricated by means of elec-trospinning. Constant conditions were held within the entire production process. It means that all samples were fabricated from collagen solution with the same chemical composition. Electrospinning conditions were also adjusted to have the same parameters, i.e. temperature, relative humidity, voltage and distance between electrodes. Finally, cross-linking procedure was also the same for all samples in-volved in the study. Elasticity of the material was assessed by means of uniaxial tensile test in a fully hydrated state of collagen samples. Internal structure of col-lagenous layers was studied by means of scanning electron microscopy. Alt-hough all technological conditions were held constant, mathematical modelling of the elastic behaviour revealed differences between samples. The results suggest that there is a certain variability of mechanical properties of electrospun hydrated collagen that is difficult to eliminate. By this fact, however, collagen is, to some extent, similar to biological tissue.

Název v anglickém jazyce

Electrospun collagen variability characterized by tensile testing

Popis výsledku anglicky

The objective of this study was to verify repeatability of the preparation process of the collagen nanofibrous layers. The layers were fabricated by means of elec-trospinning. Constant conditions were held within the entire production process. It means that all samples were fabricated from collagen solution with the same chemical composition. Electrospinning conditions were also adjusted to have the same parameters, i.e. temperature, relative humidity, voltage and distance between electrodes. Finally, cross-linking procedure was also the same for all samples in-volved in the study. Elasticity of the material was assessed by means of uniaxial tensile test in a fully hydrated state of collagen samples. Internal structure of col-lagenous layers was studied by means of scanning electron microscopy. Alt-hough all technological conditions were held constant, mathematical modelling of the elastic behaviour revealed differences between samples. The results suggest that there is a certain variability of mechanical properties of electrospun hydrated collagen that is difficult to eliminate. By this fact, however, collagen is, to some extent, similar to biological tissue.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

20302 - Applied mechanics

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

XV Mediterranean Conference on Medical and Biological Engineering and Computing – MEDICON 2019

ISBN

9783030316341

ISSN

1680-0737

e-ISSN

—

Počet stran výsledku

8

Strana od-do

1231-1238

Název nakladatele

Springer-VDI-Verlag

Místo vydání

Düsseldorf

Místo konání akce

Coimbra

Datum konání akce

26. 9. 2019

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000582693600150