Collagen in bone tissue regeneration: Focusing on the mechanical and structural constraints

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F20%3A00362120" target="_blank" >RIV/68407700:21220/20:00362120 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Collagen in bone tissue regeneration: Focusing on the mechanical and structural constraints

Popis výsledku v původním jazyce

This study demonstrates the effect of various processing conditions on the mechanical, structural and utility characteristics of collagen materials to be used for bone tissue regeneration purposes in both the microstructured and nanostructured forms. The first part presents the effective cross-linking conditions and composition of collagen microstructured composites, focusing on the collagen content and their final characteristics such as mechanical properties, internal structure and porosity in both the dry and hydrated states. The second part presents an assessment of the effective processing and cross-linking conditions of nanostructured electrospun collagen with respect to its mechanical and structural properties and the preservation of the native structure of the collagen. The third part presents the development of a biodegradable nanostructured electrospun composite layer for the treatment of implant-associated infections and improvements with respect to the rate of osseointegration.

Název v anglickém jazyce

Collagen in bone tissue regeneration: Focusing on the mechanical and structural constraints

Popis výsledku anglicky

This study demonstrates the effect of various processing conditions on the mechanical, structural and utility characteristics of collagen materials to be used for bone tissue regeneration purposes in both the microstructured and nanostructured forms. The first part presents the effective cross-linking conditions and composition of collagen microstructured composites, focusing on the collagen content and their final characteristics such as mechanical properties, internal structure and porosity in both the dry and hydrated states. The second part presents an assessment of the effective processing and cross-linking conditions of nanostructured electrospun collagen with respect to its mechanical and structural properties and the preservation of the native structure of the collagen. The third part presents the development of a biodegradable nanostructured electrospun composite layer for the treatment of implant-associated infections and improvements with respect to the rate of osseointegration.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20302 - Applied mechanics

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů