Can We Generate Systemic Arterial Hypertension by Pulsatile LVAD in Our Patients?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F11%3A00186583" target="_blank" >RIV/68407700:21230/11:00186583 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Can We Generate Systemic Arterial Hypertension by Pulsatile LVAD in Our Patients?

Popis výsledku v původním jazyce

On the basis of our personal experience of studying co-temporary scientific articles and the modelling of flow and pressure patterns in systemic vascular beds, we are encouraged to claim, that extremely small patients can experience systemic arterial hypertension generated by pulsatile a left ventricular assist device (LVAD. After implantation of LVAD with the same stroke volume (65ml), all patients have the same average flow during the ejection period, i.e. 65ml for 300ms (13 l/min!). The average flowfor the ejection period, the average blood flow during the ejection period through the entire systemic vascular bed is higher in non-physiological terms for extremely small patients and may cause iatrogenic systemic arterial hypertension. In addition wesuppose a large "stroke mismatch" (large disproportion between the primary stroke volume and the artificial one) could cause unexpected events like brain bleed

Název v anglickém jazyce

Can We Generate Systemic Arterial Hypertension by Pulsatile LVAD in Our Patients?

Popis výsledku anglicky

On the basis of our personal experience of studying co-temporary scientific articles and the modelling of flow and pressure patterns in systemic vascular beds, we are encouraged to claim, that extremely small patients can experience systemic arterial hypertension generated by pulsatile a left ventricular assist device (LVAD. After implantation of LVAD with the same stroke volume (65ml), all patients have the same average flow during the ejection period, i.e. 65ml for 300ms (13 l/min!). The average flowfor the ejection period, the average blood flow during the ejection period through the entire systemic vascular bed is higher in non-physiological terms for extremely small patients and may cause iatrogenic systemic arterial hypertension. In addition wesuppose a large "stroke mismatch" (large disproportion between the primary stroke volume and the artificial one) could cause unexpected events like brain bleed

Druh

O - Ostatní výsledky

CEP obor

JC - Počítačový hardware a software

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů