Capping agent control over the physicochemical and antibacterial properties of ZnO nanoparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F25%3A00381715" target="_blank" >RIV/68407700:21230/25:00381715 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28610/25:63594179

Výsledek na webu

<a href="https://doi.org/10.1016/j.apsusc.2025.162739" target="_blank" >https://doi.org/10.1016/j.apsusc.2025.162739</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.apsusc.2025.162739" target="_blank" >10.1016/j.apsusc.2025.162739</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Capping agent control over the physicochemical and antibacterial properties of ZnO nanoparticles

Popis výsledku v původním jazyce

Life science research has largely benefited from the use of nanoparticles (NPs), yet fundamental issues such as colloidal stability and control over NP size and shape affect NP properties and functions in biomedical applications. Here we show that including capping agents directly into zinc oxide (ZnO) NP synthesis can lead to better control of these properties and their enhanced functionality. A systematic study of the influence capping agents has on the physicochemical and antibacterial properties of ZnO NP synthesized using the microwave (MW)-assisted polyol method is presented. Primary NP size (10–20 nm) was controlled by zinc precursor concentration, and NP shape was influenced by capping agent type. Capping agents enabled control over the surface charge and water interaction properties of ZnO for further investigations involving bacteria. The superior antibacterial effect was observed using positively charged, hydrophilic HMTA-capped ZnO, yet negatively charged hydrophobic OA-capped ZnO still exhibited an antibacterial effect. These observations suggest different underlying mechanisms, and we discuss these differences with particular reference to the specific surface area of ZnO, and how this is key to bacteria-nanoparticle interactions. Appropriate selection of capping agents is crucial for the synthesis of potent ZnO NPs intended for antibacterial applications, specifically for combating resistance.

Název v anglickém jazyce

Capping agent control over the physicochemical and antibacterial properties of ZnO nanoparticles

Popis výsledku anglicky

Life science research has largely benefited from the use of nanoparticles (NPs), yet fundamental issues such as colloidal stability and control over NP size and shape affect NP properties and functions in biomedical applications. Here we show that including capping agents directly into zinc oxide (ZnO) NP synthesis can lead to better control of these properties and their enhanced functionality. A systematic study of the influence capping agents has on the physicochemical and antibacterial properties of ZnO NP synthesized using the microwave (MW)-assisted polyol method is presented. Primary NP size (10–20 nm) was controlled by zinc precursor concentration, and NP shape was influenced by capping agent type. Capping agents enabled control over the surface charge and water interaction properties of ZnO for further investigations involving bacteria. The superior antibacterial effect was observed using positively charged, hydrophilic HMTA-capped ZnO, yet negatively charged hydrophobic OA-capped ZnO still exhibited an antibacterial effect. These observations suggest different underlying mechanisms, and we discuss these differences with particular reference to the specific surface area of ZnO, and how this is key to bacteria-nanoparticle interactions. Appropriate selection of capping agents is crucial for the synthesis of potent ZnO NPs intended for antibacterial applications, specifically for combating resistance.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21002 - Nano-processes (applications on nano-scale); (biomaterials to be 2.9)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Surface Science

ISSN

0169-4332

e-ISSN

1873-5584

Svazek periodika

692

Číslo periodika v rámci svazku

May

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

—

Kód UT WoS článku

001433846000001

EID výsledku v databázi Scopus

2-s2.0-85218426225