DESIGN AND CHARACTERIZATION OF A DESK-TOP LASER PLASMA X-RAY SOURCE FOR RADIOBIOLOGY STUDIES

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

DESIGN AND CHARACTERIZATION OF A DESK-TOP LASER PLASMA X-RAY SOURCE FOR RADIOBIOLOGY STUDIES

Popis výsledku v původním jazyce

A compact desk-top laser-produced plasma source of soft X-rays for radiobiology research is presented. The source is based on a double-stream gas puff target and delivers nanosecond pulses of soft X-rays in the "water window" spectral range at a fluence of about 4.23x10(3) photon/mu m(2) per pulse on a sample placed inside the vacuum source chamber and about 2.60x10(2) photon/mu m(2) per pulse on a wet sample located outside the chamber in the He environment. The source has been used to irradiate pBR322 plasmid DNA both in vacuum and the He-environment conditions. Single and double strand breaks were quantified by gel electrophoresis. The number of strand breaks increased with increasing dose of the "water window" soft X-rays. The strand breaks of plasmid solution irradiated in helium condition may be associated with damage from water free radicals.

Název v anglickém jazyce

DESIGN AND CHARACTERIZATION OF A DESK-TOP LASER PLASMA X-RAY SOURCE FOR RADIOBIOLOGY STUDIES

Popis výsledku anglicky

A compact desk-top laser-produced plasma source of soft X-rays for radiobiology research is presented. The source is based on a double-stream gas puff target and delivers nanosecond pulses of soft X-rays in the "water window" spectral range at a fluence of about 4.23x10(3) photon/mu m(2) per pulse on a sample placed inside the vacuum source chamber and about 2.60x10(2) photon/mu m(2) per pulse on a wet sample located outside the chamber in the He environment. The source has been used to irradiate pBR322 plasmid DNA both in vacuum and the He-environment conditions. Single and double strand breaks were quantified by gel electrophoresis. The number of strand breaks increased with increasing dose of the "water window" soft X-rays. The strand breaks of plasmid solution irradiated in helium condition may be associated with damage from water free radicals.

Druh

D - Stať ve sborníku

CEP obor

BH - Optika, masery a lasery

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

RAD 2015: THE THIRD INTERNATIONAL CONFERENCE ON RADIATION AND APPLICATIONS IN VARIOUS FIELDS OF RESEARCH

ISBN

978-86-80300-01-6

ISSN

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e-ISSN

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Počet stran výsledku

6

Strana od-do

495-500

Název nakladatele

RAD Association, Niš, Serbia

Místo vydání

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Místo konání akce

Budva, Montenegro

Datum konání akce

8. 6. 2015

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000387979700103