Revisiting the biosensing potential of a plasmonic metamaterial supporting a guided mode

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F17%3A00319290" target="_blank" >RIV/68407700:21340/17:00319290 - isvavai.cz</a>

Výsledek na webu

<a href="http://spie.org/EOO/conferencedetails/optical-sensors?SSO=1" target="_blank" >http://spie.org/EOO/conferencedetails/optical-sensors?SSO=1</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Revisiting the biosensing potential of a plasmonic metamaterial supporting a guided mode

Popis výsledku v původním jazyce

With rapid developments in the field of nanoplasmonics, a broad variety of novel plasmonic phenomena on various nanostructures have been introduced as alternative approaches to surface plasmon resonance (SPR) biosensing. Recently, a plasmonic metamaterial comprised of dense packed plasmonic nanorods supporting a guided mode has been proposed for sensing purposes, showing extremely high sensitivity to bulk refractive index. In this work, we revisit the sensing potential of this type of sensing structure through investigation via approaches relevant for biosensing applications. We examine the optical response to refractive index changes confined within a small volume at the proximity of the active sensing surface and furthermore, investigate correlations with both bulk sensitivity and the distribution of the electromagnetic field. We will discuss the geometrical parameters of the plasmonic structure as well as the critical role of the substrate. Apart from the optical properties, we also consider aspects related to the mass-transport of the analyte to the binding sites on the active sensing area, studied in terms of kinetic parameters of the assay. The optical performance was calculated by a recently developed (approximate) analytical model based on effective medium approximation and transfer-matrix method; results are compared with the rigorous coupled-wave analysis. The mass-transfer performance is estimated using a recently developed analytical model, verified both by numerical simulation as well as experiment. The combination of these models provides a design guideline towards such sensors: we show that under proper conditions, the biosensing potential of a nanoparticle array can exceed that of a conventional SPR sensing structure (based on the continuous gold layer) by over an order of magnitude.

Název v anglickém jazyce

Revisiting the biosensing potential of a plasmonic metamaterial supporting a guided mode

Popis výsledku anglicky

With rapid developments in the field of nanoplasmonics, a broad variety of novel plasmonic phenomena on various nanostructures have been introduced as alternative approaches to surface plasmon resonance (SPR) biosensing. Recently, a plasmonic metamaterial comprised of dense packed plasmonic nanorods supporting a guided mode has been proposed for sensing purposes, showing extremely high sensitivity to bulk refractive index. In this work, we revisit the sensing potential of this type of sensing structure through investigation via approaches relevant for biosensing applications. We examine the optical response to refractive index changes confined within a small volume at the proximity of the active sensing surface and furthermore, investigate correlations with both bulk sensitivity and the distribution of the electromagnetic field. We will discuss the geometrical parameters of the plasmonic structure as well as the critical role of the substrate. Apart from the optical properties, we also consider aspects related to the mass-transport of the analyte to the binding sites on the active sensing area, studied in terms of kinetic parameters of the assay. The optical performance was calculated by a recently developed (approximate) analytical model based on effective medium approximation and transfer-matrix method; results are compared with the rigorous coupled-wave analysis. The mass-transfer performance is estimated using a recently developed analytical model, verified both by numerical simulation as well as experiment. The combination of these models provides a design guideline towards such sensors: we show that under proper conditions, the biosensing potential of a nanoparticle array can exceed that of a conventional SPR sensing structure (based on the continuous gold layer) by over an order of magnitude.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10306 - Optics (including laser optics and quantum optics)

Projekt

<a href="/cs/project/GBP205%2F12%2FG118" target="_blank" >GBP205/12/G118: Nanobiofotonika pro medicínu budoucnosti</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů