SEPARATION OF Fr-221 FROM Ac-225 USING DIGLYCOLAMIDE SOLID EXTRACTANTS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F22%3A00361727" target="_blank" >RIV/68407700:21340/22:00361727 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

SEPARATION OF Fr-221 FROM Ac-225 USING DIGLYCOLAMIDE SOLID EXTRACTANTS

Popis výsledku v původním jazyce

Diglycolamides are frequently used as extraction agents in many fields of nuclear and separation chemistry including nuclear waste management, nuclear fuel reprocessing, radioanalytical chemistry, radioecology or nuclear medicine. They are tridentate ligands with extraction abilities to extract trivalent ions, mainly lanthanides and actinides. This ability can be beneficial in separation of radionuclides for nuclear medicine. In practise, diglycolamides are used for example in separation of clinical 223Ra from 227Ac/227Th/223Ra mixtures. Another important medicinal radionuclide of recent years, 255Ac, is separated from its mother radionuclide 225Ra using diglycolamides as well. The first decay product of 225Ac transmutation is 221Fr with a half-life of 5 min decaying to 213Bi. As a monovalent ion it could be easily separable from 225Ac. In this work two most common diglycolamides, TODGA and isoTODGA, were tested for separation of 221Fr from 225Ac in preliminary studies. Diglycolamides were immobilised on polyacrylonitrile beads to form solid extractants TODGA-PAN and isoTODGA-PAN. The loading of such solid extractants was 40 %. Batch sorption experiments with both solid extractants were performed in both hydrochloric and nitric acid media. The weight distribution coefficients of 225Ac were determined. As expected, especially high weight distribution coefficients were achieved for both solid extractants in higher concentrations of nitric acid. Subsequently, the most promising conditions of 225Ac sorption were applied in column experiments in order to evaluate 221Fr elution.

Název v anglickém jazyce

SEPARATION OF Fr-221 FROM Ac-225 USING DIGLYCOLAMIDE SOLID EXTRACTANTS

Popis výsledku anglicky

Diglycolamides are frequently used as extraction agents in many fields of nuclear and separation chemistry including nuclear waste management, nuclear fuel reprocessing, radioanalytical chemistry, radioecology or nuclear medicine. They are tridentate ligands with extraction abilities to extract trivalent ions, mainly lanthanides and actinides. This ability can be beneficial in separation of radionuclides for nuclear medicine. In practise, diglycolamides are used for example in separation of clinical 223Ra from 227Ac/227Th/223Ra mixtures. Another important medicinal radionuclide of recent years, 255Ac, is separated from its mother radionuclide 225Ra using diglycolamides as well. The first decay product of 225Ac transmutation is 221Fr with a half-life of 5 min decaying to 213Bi. As a monovalent ion it could be easily separable from 225Ac. In this work two most common diglycolamides, TODGA and isoTODGA, were tested for separation of 221Fr from 225Ac in preliminary studies. Diglycolamides were immobilised on polyacrylonitrile beads to form solid extractants TODGA-PAN and isoTODGA-PAN. The loading of such solid extractants was 40 %. Batch sorption experiments with both solid extractants were performed in both hydrochloric and nitric acid media. The weight distribution coefficients of 225Ac were determined. As expected, especially high weight distribution coefficients were achieved for both solid extractants in higher concentrations of nitric acid. Subsequently, the most promising conditions of 225Ac sorption were applied in column experiments in order to evaluate 221Fr elution.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10402 - Inorganic and nuclear chemistry

Projekt

<a href="/cs/project/TJ04000129" target="_blank" >TJ04000129: Separace radionuklidů pro cílenou alfa částicovou terapii</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů