PREPARATION AND CHARACTERIZATION OF ΑZIRCONIUM PHOSPHATE AS A PERSPECTIVE MATERIAL FOR SEPARATION OF MEDICINAL RADIONUCLIDES

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21340%2F22%3A00361728" target="_blank" >RIV/68407700:21340/22:00361728 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

PREPARATION AND CHARACTERIZATION OF ΑZIRCONIUM PHOSPHATE AS A PERSPECTIVE MATERIAL FOR SEPARATION OF MEDICINAL RADIONUCLIDES

Popis výsledku v původním jazyce

Zirconium phosphate (ZrP) has been the subject of research for many years. The interest for this material is based on its outstanding physicochemical properties, both in its amorphous and crystalline phases. It is necessary to unequivocally highlight its extremly high ion-exchange capacity, very good biocompatibility and stability, and good thermal and radiation stability. At the same time, it should be noted that the synthesis of ZrP and its subsequent functionalization is very simple. All of this makes ZrP perspective candidate for a wide range of applications in chemistry, health and nuclear industry, but especially in nuclear medicine area for example as a potentional drug delivery system, ion-exchanger for sources of high purity radionuclides. Zirconium phosphate, specifically its alpha alotropic modification (α-ZrP), was prepared by refluxing an aqueous solution of oxychloride octahydrate and sodium dihydrogenphosphate monohydrate solution in hydrochloric acid. The prepared α-ZrP was completely characterized using infra red and Raman spectroscopy, X-ray powder difraction, DTA and TG analysis, FEGSEM/SE, TEM/BF 2D-SAED and TEM/EDX analysis. Finally, experiments studying mechanism of sorption on a surface of α-ZrP and characterizing the surface of α-ZrP by its active soprtion sites and functional groups using potentiometric titrations in pH range 2-11 was carried out.

Název v anglickém jazyce

PREPARATION AND CHARACTERIZATION OF ΑZIRCONIUM PHOSPHATE AS A PERSPECTIVE MATERIAL FOR SEPARATION OF MEDICINAL RADIONUCLIDES

Popis výsledku anglicky

Zirconium phosphate (ZrP) has been the subject of research for many years. The interest for this material is based on its outstanding physicochemical properties, both in its amorphous and crystalline phases. It is necessary to unequivocally highlight its extremly high ion-exchange capacity, very good biocompatibility and stability, and good thermal and radiation stability. At the same time, it should be noted that the synthesis of ZrP and its subsequent functionalization is very simple. All of this makes ZrP perspective candidate for a wide range of applications in chemistry, health and nuclear industry, but especially in nuclear medicine area for example as a potentional drug delivery system, ion-exchanger for sources of high purity radionuclides. Zirconium phosphate, specifically its alpha alotropic modification (α-ZrP), was prepared by refluxing an aqueous solution of oxychloride octahydrate and sodium dihydrogenphosphate monohydrate solution in hydrochloric acid. The prepared α-ZrP was completely characterized using infra red and Raman spectroscopy, X-ray powder difraction, DTA and TG analysis, FEGSEM/SE, TEM/BF 2D-SAED and TEM/EDX analysis. Finally, experiments studying mechanism of sorption on a surface of α-ZrP and characterizing the surface of α-ZrP by its active soprtion sites and functional groups using potentiometric titrations in pH range 2-11 was carried out.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10402 - Inorganic and nuclear chemistry

Projekt

<a href="/cs/project/TJ04000129" target="_blank" >TJ04000129: Separace radionuklidů pro cílenou alfa částicovou terapii</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů